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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
- 保质期:
参照说明书可保存1-2年
- 英文名:
GLUT2 Peptide
- 库存:
一定量库存
- 供应商:
华拓生物
- 规格:
0.1 mg
| 产品名称: | GLUT2 Peptide |
| 产品链接: | http://www.abbiotec.com/peptides/glut2-peptide |
| 货号: | 300121 |
| 规格: | 0.1 mg |
| 产品描述: | Glucose transporter type 2 (GLUT2 or SLC2A2) is a facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells. GLUT2 is also part of the glucose-sensing mechanism of the beta cell and participate with the Na+/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. Defects in GLUT2 are the cause of Fanconi-Bickel syndrome, characterized by hepatorenal glycogen accumulation, proximal renal tubular dysfunction, and impaired utilization of glucose and galactose. |
| 序列: | The synthetic peptide used to raise the antibody Cat. No. 250672 is selected from a sequence within the C-term region of human GLUT2. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended. |
| 分子式: | |
| 分子量: | |
| 纯度: | Purity > 80% by HPLC |
| 别名: | Solute carrier family 2 facilitated glucose transporter member 2; Glucose transporter type 2 liver; GLUT-2; SLC2A2; GLUT2 |
| 形态: | Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect. |
| 溶解方法: | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| 保存方法: | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. |
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Two dimensional peptide mapping
This specfic protocol is the latest incarnation of peptide mapping procedures that have been developed here in the TVL/MBVL of the Salk Institute over the last 20 years. Wade Gibson developed the first peptide mapping protocol
Measurement of Contraction-Stimulated GLUT-4 Translocation in Isolated Skeletal Muscle
-sensitive cells, such as heart, skeletal muscle, and adipose tissue, glucose transport is mediated by two members of this family, termed GLUT-1 and GLUT-4. Of these two transporters, GLUT-1 is found primarily in the plasma membrane and functions
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