- ￥600 - 1600
- Abbiotec
- 美国
- 350496
- 2025年07月16日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
- 保质期：
参照说明书可保存1-2年
- 英文名：
E-cadherin Peptide
- 库存：
一定量库存
- 供应商：
华拓生物
- 规格：
0.1 mg
| 产品名称： | E-cadherin Peptide |
| 产品链接： | http://www.abbiotec.com/peptides/e-cadherin-peptide |
| 货号： | 350496 |
| 规格： | 0.1 mg |
| 产品描述： | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. E-cadherin (CDH1) is involved in mechanisms regulating cell-cell adhesion, mobility and proliferation of epithelial cells. CDH1 has a potent invasive suppressor role. CDH1 binds to integrin alpha-E/beta-7. Defects in CDH1 are the cause of gastric, endometrial, breast, ovary and thyroid cancers. This antibody may cross-react with cadherin-2, 3 and 4. |
| 序列： | The synthetic peptide used to raise the antibody Cat. No. 200134 is selected from a sequence within the C-term region of human E-cadherin. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended. |
| 分子式： | C89H125N25O34S1 |
| 分子量： | 2121.1 g/mol |
| 纯度： | Purity > 80% by HPLC |
| 别名： | Epithelial cadherin; Uvomorulin; Cadherin-1; CAM 120/80; CD324 antigen; CDH1; CDHE; UVO |
| 形态： | Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect. |
| 溶解方法： | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| 保存方法： | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. |
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文献和实验二个以上的α -氨基酸以肽键连接起来而形成的化合物。根据构成氨基酸的数目 2、 3、 4……叫做二肽（ dipeptide）、三肽、四肽……。大体上由 10以下的肽键形成的肽总称为寡肽 （ Oligopeptide），由多数肽键构成的肽总称为多肽。每个肽按照构成它的氨基酸的名称，从具有游离α -氨基的末端氨基酸依次命名。例如 称为甘氨酰丙氨酸的二肽。蛋白质是由一条或几条长链状多肽构成的。象谷胱甘肽和肌肽那样的低
Two dimensional peptide mapping
This specfic protocol is the latest incarnation of peptide mapping procedures that have been developed here in the TVL/MBVL of the Salk Institute over the last 20 years. Wade Gibson developed the first peptide mapping protocol
Tracking the Transport of E-Cadherin to and From the Plasma Membrane
, it is also a key occurrence in many diseases, including cancers of epithelial origin E-cadherin is a central component of adherens junctions (AJs), which act as structural and signaling hubs in epithelial cells that oppose EMT. The loss of E-cadherin
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