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- 详细信息
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
Crocin
- 库存:
10
- 供应商:
TargetMol
- CAS号:
42553-65-1
- 规格:
20 mg/1 mL
| 规格: | 20 mg | 产品价格: | ¥380.0 |
|---|---|---|---|
| 规格: | 1 mL | 产品价格: | ¥350.0 |
Product Introduction
Bioactivity
英文名:Crocin
描述:Crocin (Gardenia Yellow) is a water-soluble carotenoid pigment of saffron (Crocus sativus L. ) that has been used as a spice for flavoring and coloring food preparations, and in Chinese traditional medicine as an anodyne or tranquilizer. Crocin suppresses tumor necrosis factor (TNF)alpha-induced apoptosis of pheochromocytoma (PC12) cells by modulating mRNA expressions of Bcl-2 family proteins, which trigger downstream signals culminating in caspase-3 activation followed by cell death. Crocin prevented the activation of nSMase by enhancing the transcription of gamma-glutamylcysteinyl synthase, which contributes to a stable glutathione supply that blocks the activity of nSMase.

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