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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
Ponatinib
- 库存:
10
- 供应商:
TargetMol
- CAS号:
943319-70-8
- 规格:
10 mg/200 mg/50 mg/1 mL/100 mg
| 规格: | 10 mg | 产品价格: | ¥669.0 |
|---|---|---|---|
| 规格: | 200 mg | 产品价格: | ¥3940.0 |
| 规格: | 50 mg | 产品价格: | ¥1900.0 |
| 规格: | 1 mL | 产品价格: | ¥616.0 |
| 规格: | 100 mg | 产品价格: | ¥2683.0 |
Product Introduction
Bioactivity
英文名:Ponatinib
描述:Ponatinib (AP24534) is a multi-targeted kinase inhibitor with oral activity that inhibits Abl, PDGFRα, VEGFR2, FGFR1, and Src (IC50=0.37/1.1/1.5/2.2/5.4 nM). Ponatinib has antitumor activity for the treatment of chronic granulocytic leukemia in adults. leukemia.

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文献和实验strategy to identify the spectrum of resistance-conferring mutations, which has helped in designing the next-generation BCR/ABL inhibitors such as Nilotinib, Dasatinib, and Ponatinib. Here we provide a detailed methodology for the screen
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