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Fludrocortisone acetate

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  • ¥247 - 338
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  • 美国
  • T1666
  • 2025年08月16日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      零下80~20°C

    • 保质期

      Powder: -20°C for 3 years In solvent: -80°C for 2 years

    • 英文名

      Fludrocortisone acetate

    • 库存

      10

    • 供应商

      TargetMol

    • CAS号

      514-36-3

    • 规格

      200 mg/100 mg/1 mL

    规格:200 mg产品价格:¥338.0
    规格:100 mg产品价格:¥247.0
    规格:1 mL产品价格:¥272.0

    Product Introduction
    Bioactivity


    英文名:Fludrocortisone acetate

    描述:Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and subsequently initiates the transcription of glucocorticoid-responsive genes such as lipocortins to inhibit phospholipase A2 (PLA2). Fludrocortisone acetate is the acetate salt of a synthetic fluorinated corticosteroid with anti-inflammatory and antiallergic activities. Inhibition of PLA2 activity prevents the release of arachidonic acid, a precursor of eicosanoids such as prostaglandins and leukotrienes; eicosanoids are important mediators in the pro-inflammatory response mechanism. As a mineralocorticoid-receptor agonist, this agent stimulates Na+ reabsorption and water retention and K+ and H+ secretion in the distal tubules and collecting ducts of the kidney.



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    图标文献和实验
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    • Acetate Kinase From Methanosarcina thermophila, a Key Enzyme for Methanogenesis

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    Fludrocortisone acetate
    ¥247 - 338