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- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名:
Corylifol-A; Corylinin
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- 规格:
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg/50 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥1289.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥628.0 |
| 规格: | 5 mg | 产品价格: | ¥1500.0 |
| 规格: | 10 mg | 产品价格: | ¥2250.0 |
| 规格: | 25 mg | 产品价格: | ¥3600.0 |
| 规格: | 50 mg | 产品价格: | ¥5000.0 |
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Corylifol A
CAS No. : 775351-88-7
MCE 国际站:Corylifol A
产品活性:Corylifol A 能够抑制IL-6 诱导的 STAT3 的激活和磷酸化,其IC50 值为0.81 μM。
研究领域:JAK/STAT Signaling | Stem Cell/Wnt
作用靶点:STAT
In Vitro: Corylifol A shows an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells with IC50 value of 0.81±0.15 μM, also inhibits STAT3 phosphorylation induced by IL-6 in Hep3B cells. Corylifol A inhibits SARA PLpro in a dose-dependent manner with IC50s ranging between 4.2 and 38.4 μM. Corylifol A is found to be a naturally occurring potent inhibitor of hCE2, with low Ki values ranging from 0.62 μM to 3.89 μM.
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