Sulfaguanidine

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Sulfaguanidine

CAS No. : 57-67-0

MCE 国际站：Sulfaguanidine

产品活性：Sulfaguanidine 是一种具有口服活性的磺胺类抗菌剂/抗生素。Sulfaguanidine 可用于肠道感染，例如细菌性痢疾的研究。

研究领域：Anti-infection

作用靶点：Bacterial  |  Antibiotic

In Vivo: Sulfaguanidine (2.5 mg/kg; i.v.) exhibits CL_t (adult 0.29, neonate 0.14 L/h/kg), AUC_0-∞ (adult 8.18, neonate 20.46 μg•h/mL), and Vd_ss (adult 0.65, neonate 0.59 L/kg) in rats.
Sulfaguanidine (2.5 mg/kg; p.o.) exhibits absolute bioavailability (adult 12.76%, neonate 57.86%), C_max (adult 0.41, neonate 3.56 μg/mL), and T_max (adult 1.67, neonate 1.50 h) in rats.

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