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- 详细信息
- 技术资料
- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
13463-41-7
- 规格:
10 mM * 1 mL/500 mg/1 g/5 g
| 规格: | 10 mM * 1 mL | 产品价格: | ¥500.0 |
|---|---|---|---|
| 规格: | 500 mg | 产品价格: | ¥400.0 |
| 规格: | 1 g | 产品价格: | ¥558.0 |
| 规格: | 5 g | 产品价格: | ¥900.0 |
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Zinc Pyrithione
CAS No. : 13463-41-7
MCE 国际站:Zinc Pyrithione
产品活性:Zinc Pyrithione 能抗真菌和细菌,可通过阻断质子泵扰乱膜运输。Zinc Pyrithione 也是一种铜离子载体,可将铜输送到细胞中,是研究铜死亡 (cuproptosis) 的有用工具。
研究领域:Membrane Transporter/Ion Channel | Anti-infection
作用靶点:Proton Pump | Bacterial | Fungal
In Vitro: Zinc pyrithione is considered as a coordination complex of zinc. The pyrithione ligands, which are formally monoanions, are chelated to Zn 2+ via oxygen and sulfur centers. In the crystalline state, zinc pyrithione exists as a centrosymmetric dimer, where each zinc is bonded to two sulfur and three oxygen centers. In solution, however, the dimers dissociate via scission of one Zn-O bond. Zinc pyrithione, which is a dimer but is probably biologically active as a monomer, induces plasma membrane depolarization with half-maximal effect (K1/2) of about 0.3 mM.
Zinc Pyrithione (10 nM-10 μM; 72 hours) significantly induces cell death in AAVS1 cells.
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