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- 保存条件:
4°C, sealed storage, away from moisture
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
366-70-1
- 规格:
10 mM * 1 mL/100 mg/500 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥693.0 |
|---|---|---|---|
| 规格: | 100 mg | 产品价格: | ¥630.0 |
| 规格: | 500 mg | 产品价格: | ¥1880.0 |
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Procarbazine Hydrochloride
CAS No. : 366-70-1
MCE 国际站:Procarbazine Hydrochloride
产品活性:Procarbazine Hydrochloride 是一种烷化剂 (alkylator),具有抗肿瘤的作用。
研究领域:Cell Cycle/DNA Damage
作用靶点:DNA Alkylator/Crosslinker
In Vitro: Procarbazine Hydrochloride is an anticancer agent. Procarbazine is not cytotoxic to the LI 210 cells which lack cytochrome P-450 or monoamine oxidase activity.
In Vivo: Procarbazine Hydrochloride (50 mg/kg, i.p.) causes micronuclei in hematopoietic cells, but does not increase the lacZ mutant frequency (MF) in bone marrow of mice, similar to that in liver, testis, spleen, kidney, and lung. Procarbazine Hydrochloride (50 mg/kg, i.p.) has positive effect on lung, bone marrow, and spleen for carcinogenesis. Procarbazine (450 mg/kg) significantly decreases testicular and epididymal weight and drastically reduces haploid cells and spermatogenic arrest in hamster.
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