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- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
SM 7338 trihydrate
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
119478-56-7
- 规格：
10 mM * 1 mL/50 mg/100 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥880.0 |
|---|---|---|---|
| 规格： | 50 mg | 产品价格： | ￥800.0 |
| 规格： | 100 mg | 产品价格： | ￥1100.0 |
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Meropenem trihydrate
CAS No. : 119478-56-7
MCE 国际站：Meropenem trihydrate
产品活性：Meropenem trihydrate (SM 7338 trihydrate) 是一种具有广谱抗菌活性的碳青霉烯抗生素。Meropenem trihydrate 对敏感和耐药的淋病奈瑟氏球菌 (MIC 值为 0.02-0.06 mg/mL)，流感嗜血杆菌 (MIC 值为 0.03-0.12 mg/mL) 和杜克氏杆菌 (MIC 值为 0.015-0.12 mg/mL) 具有活性。
研究领域：Anti-infection
作用靶点：Bacterial | Antibiotic
In Vitro: Meropenem is intrinsically stable to dehydropeptidase-1 (DHP-1) degradation and Meropenem acts by inhibiting bacterial cell wall synthesis by binding to and inactivating penicillin-binding proteins (PBPs). Meropenem possesses broad-spectrum in vitro activity, which includes activity against many Gram-positive, Gram-negative and anaerobic bacteria; Meropenem lacks activity against Enterococcus faecium, methicillin-resistant Staphylococcus aureus and Stenotrophomonas maltophilia.
In Vivo: Meropenem (60 mg/kg; intraperitoneal injection; once; SD rats) treatment significantly reduces the incidence of pancreatic infection.
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文献和实验%以上(n=15)。日内RSD≤6.22%，日间RSD≤3.69%。结论 本方法简单、快速、准确，可用于美罗培南的浓度测定和药动学研究。 【关键词】 美罗培南； 高效液相色谱法； 胆汁 ABSTRACT Objective To establish a high performance liquid chromatography (HPLC) method to assay the concentration of meropenem in bile. Methods
Detection of Glycoproteins on Blot
Sodium acetate Buffer (200mM, pH 5.5): Prepare a 200 mM solution of sodium acetate by disolving 12.0 gam of sodium acetate trihydrate in 440 ml of dw. Prepare a 200mM solution of acetic acid by dissolving 690ul of glacial acetic acid to 60 ml
，30μg)、头孢吡肟(Cefepime，30μg)、亚胺培南(Imipenem，10μg)、美罗培南(Meropenem，10μg)、庆大霉素(Gentamycin，10μg)、复方磺胺(Trimethoprim/sulfamethoxazole, 12.5/23.75μg)、哌拉西林/他唑巴坦(Piperacillin/tazobactam，100/10μg)、头孢哌酮/舒巴坦(Cefoperazone/sulbactam，75/75μg)、氨苄西林/舒巴坦(Ampicillin
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