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- 保存条件:
4°C, sealed storage, away from moisture
- 英文名:
Chlorphenamine maleate
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
113-92-8
- 规格:
10 mM * 1 mL/1 g/5 g
| 规格: | 10 mM * 1 mL | 产品价格: | ¥220.0 |
|---|---|---|---|
| 规格: | 1 g | 产品价格: | ¥200.0 |
| 规格: | 5 g | 产品价格: | ¥450.0 |
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Chlorpheniramine maleate
CAS No. : 113-92-8
MCE 国际站:Chlorpheniramine maleate
产品活性:Chlorpheniramine maleate是组胺 H1 受体拮抗剂 (IC50: 12 nM)。
研究领域:GPCR/G Protein | Neuronal Signaling | Immunology/Inflammation
作用靶点:Histamine Receptor
In Vitro: Chlorpheniramine maleate shows antimalarial activity against P. falciparum (IC50: 61.2 and 3.9 μM for D6 and Dd2 strain).
Chlorpheniramine maleate reduces the proton currents (IC50: 43 μM) in BV2 microglial cells.
In Vivo: Chlorpheniramine maleate (10 mg/kg, p.o) inhibits scratching in Ovalbumin (HY-W250978)-challenged BALB/c mice.
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文献和实验与氨茶碱复合物,预防晕动病,行前半小时服50mg。 盐酸异丙嗪(promethazine hydrochloride;非那根,phenergan)片剂,1.25~25mg/次,2~3次/日。注射剂,25~50mg/次,肌内或静脉注射。 盐酸吡苄明(pyribenzamine hydrochloride去敏灵,扑敏宁)片剂,25~50mg/次,3次/日。 马来酸氯苯那敏(chlorpheniramine maleate,扑尔敏)片剂,4mg/次,3次/日,小儿0.35mg
离子浓度下降。用药4周,在内窥镜检查下,十二指肠溃疡愈合率为77%~92%。晚饭时1次给药疗效与一日多次给药的疗效相仿或更佳。对 胃溃疡 疗效发挥较慢,用药8周愈合率为75%~88%。雷尼替丁尼扎替丁抑制胃酸分泌作用比西米替丁强4~10倍,法莫丁比西米替丁强20~50倍。 【体内过程】本类药物口服吸收良好,但首关消除使生物利用度降为50%~60%。消除t1/2尼扎替丁为1.3小时,其他三药为2~3小时。大部分药物以原形经肾排出,但肝功能不良者雷尼替丁半衰期明显延长
MicroRNA和siRNA克隆规程(MicroRNA and siRNA Cloning Protocol)
RNA Cloning Method Flowchart Extract total RNA containing small RNAs. Check quality on denaturing gel with EtBr staining 5" End label RNA markers 18.113 (18mer) and 44.12 (24mer
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