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- 详细信息
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
79-57-2
- 规格：
10 mM * 1 mL/50 mg/100 mg/500 mg/1 g
| 规格： | 10 mM * 1 mL | 产品价格： | ￥440.0 |
|---|---|---|---|
| 规格： | 50 mg | 产品价格： | ￥400.0 |
| 规格： | 100 mg | 产品价格： | ￥700.0 |
| 规格： | 500 mg | 产品价格： | ￥1400.0 |
| 规格： | 1 g | 产品价格： | ￥2000.0 |
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Oxytetracycline
CAS No. : 79-57-2
MCE 国际站：Oxytetracycline
产品活性：Oxytetracycline 是一种属于四环素类的抗生素。Oxytetracycline 强力抑制革兰氏阴性和革兰氏阳性细菌。Oxytetracycline 是一种蛋白质合成抑制剂，可阻止 aminoacil-tRNA 与复杂的核糖体 RNA 结合。Oxytetracycline 还具有抗 HSV-1 的活性。
研究领域：Anti-infection | Metabolic Enzyme/Protease
作用靶点：Bacterial | HSV | Endogenous Metabolite | Antibiotic
In Vitro: Oxytetracycline is an important member of the bacterial aromatic polyketide family, which is a structurally diverse class of natural products. Oxytetracycline is synthesized by a type II polyketide synthase that generates the poly-beta-ketone backbone through successive decarboxylative condensation of malonyl-CoA extender units, followed by modifications by cyclases, oxygenases, transferases, and additional tailoring enzymes.
In Vivo: The effects of administration a therapeutic dose of Oxytetracycline (82.8 mg/kg of bw to 1 % bw/day) for 10 days are species specific. Oxytetracycline increases the relative liver weight in Morone chrysops x M. saxatilis, the enzymatic activity of CYP3A4 in Ictalurus punctatus, protein expression of CYP3A4 in Oreochromis niloticus and depleted the hepatic CYP3A4 in the latter.
For Oxytetracycline, the limits are 100 μg/kg in muscle and milk, 200 μg/kg in egg, 300 μg/kg in liver and 600 μg/kg in kidney. Oxytetracycline (OTC) is administered to fish as medicated feed at concentrations ranging from 35 to 75 mg a.i kg-1 biomass day-1 for 7-14 days.
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