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- 详细信息
- 技术资料
- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名:
NTZ; NSC 697855
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
55981-09-4
- 规格:
10 mM * 1 mL/1 mg/5 mg/10 mg/50 mg/100 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥500.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥140.0 |
| 规格: | 5 mg | 产品价格: | ¥281.0 |
| 规格: | 10 mg | 产品价格: | ¥450.0 |
| 规格: | 50 mg | 产品价格: | ¥1469.0 |
| 规格: | 100 mg | 产品价格: | ¥1989.0 |
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Nitazoxanide
CAS No. : 55981-09-4
MCE 国际站:Nitazoxanide
产品活性:Nitazoxanide (NTZ) 是一种广谱驱虫剂 (anthelmintic),对感染动物和人类的各种蠕虫、原生动物和肠道细菌都具有作用活性。 Nitazoxanide 在无菌培养中抑制 Giardia lamblia 滋养体增殖,IC50 为 2.4 μM。Nitazoxanide 可用于寄生虫性 (parasitic) 胃肠炎的研究。Nitazoxanide还具有抗病毒特性。 Nitazoxanide 在小鼠模型中显示出抗日本脑炎病毒 (JEV) 活性。
研究领域:Anti-infection | Autophagy
作用靶点:Parasite | Influenza Virus | Autophagy
In Vitro: Giardia lamblia, a flagellated protozoan, is the most common causative agent of persistent diarrhea worldwide.
?Nitazoxanide exhibits effect on G. lamblia trophozoite proliferation in axenic culture with an IC50 of 2.4 μM.
In Vivo: Nitazoxanide exhibits a wide spectrum of in vivo activity against a broad spectrum of intestinal parasites, such as Giardia lamblia, Entamoeba histolytica, Trichomonas vaginalis, the apicomplexan Cryptosporidium parvum, and enteric bacteria infecting animals and humans.
?Nitazoxanide (50, 75 or 100 mg/kg/day; administered daily by intragastric for up to 25 days) reduces the mortality of Japanese encephalitis virus (JEV) strain-infected mice and protected mice from a lethal dose challenge of JEV.
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