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- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名:
Qinghaosu; NSC 369397
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
63968-64-9
- 规格:
10 mM * 1 mL/200 mg/500 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥737.0 |
|---|---|---|---|
| 规格: | 200 mg | 产品价格: | ¥670.0 |
| 规格: | 500 mg | 产品价格: | ¥1116.0 |
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Artemisinin
CAS No. : 63968-64-9
MCE 国际站:Artemisinin
产品活性:Artemisinin (Qinghaosu) 是一种倍半萜烯内酯,从黄花蒿 (Artemisia annua L.) 植物的地上部分分离的抗疟疾活性分子。Artemisinin 以剂量依赖性方式降低 pAKT 来抑制 AKT 信号通路。Artemisinin 可减少癌细胞的增殖,迁移,侵袭,肿瘤发生和转移,同时 Artemisinin 有神经保护作用。
研究领域:Anti-infection | PI3K/Akt/mTOR | Apoptosis
作用靶点:HCV | Parasite | Akt | Ferroptosis
In Vitro: Artemisinin (Qinghaosu) (25 or 50 μM; 24 hours) concentration-dependently suppresses Aβ25-35 induced cytotoxicity in PC12 cells.
Artemisinin (1-100 μM; 24 hours) selectively inhibits cancer cell growth in a dose-dependent manner with IC50 values of 31.30 ± 0.73 μM in UMRC-2 cells and 23.97 ± 0.92 CAKI-2 cells.
Artemisinin (25, 50 μM; 24 hours) suppresses the phosphorylation of AKT in UMRC-2 and CAKI-2 cells in a dose-dependent manner.
In Vivo: Artemisinin (gavage; 20 mg/kg/day; for two weeks) suppresses UMRC-2 xenograft tumor growth.
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文献和实验Malaria is a major disease in many countries and, according to an estimation by the World Health Organization (WHO), approx 300–500 million people contract malaria yearly and almost 2 million die annually (1 ). Controlling malaria
疟原虫 Malaria Parasites(Plasmodium)
is the same as that for P. vivax except it is not necessary to give primaquine to those patients with P. malariae Artemisinins.Artemisinin has been used for many years by the Chinese as a traditional treatment for fever and malaria. It is a sesquiterpene lactone derived
14. 单词首个字母大写 常见问题:单词首个字母大小写错误。 解决办法:正确使用大小写。 详解:单词首个字母大写适用于句首、城市名、公司名、人名、商标名和中药名等。但药物化学名在句中首个字母不大写,如 Qinghaosu vs artemisinin和Biltricide vs praziquantel。 15. 人名称呼 常见问题:句中 professor 的首个字母大写。 解决办法:使用小写。 详解:正文
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