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- 详细信息
- 技术资料
- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名:
CI-825; Deoxycoformycin
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- 规格:
10 mM * 1 mL/5 mg/10 mg/25 mg/50 mg/100 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥660.0 |
|---|---|---|---|
| 规格: | 5 mg | 产品价格: | ¥534.0 |
| 规格: | 10 mg | 产品价格: | ¥846.0 |
| 规格: | 25 mg | 产品价格: | ¥1907.0 |
| 规格: | 50 mg | 产品价格: | ¥3338.0 |
| 规格: | 100 mg | 产品价格: | ¥4673.0 |
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Pentostatin
CAS No. : 53910-25-1
MCE 国际站:Pentostatin
产品活性:Pentostatin (CI-825; Deoxycoformycin) 是一种高效,不可逆的腺苷脱氨酶抑制剂,Ki 值为 2.5 pM。
研究领域:Metabolic Enzyme/Protease | Anti-infection
作用靶点:Adenosine Deaminase | Antibiotic
In Vivo: In ECP and Pentostatin (CI-825; Deoxycoformycin; 4 mg/m2, i.v.) treatment, all dogs develop granulocytopenia with <500 granulocytes/μL from day 4. Thrombocytopenia (<20,000 platelets/μL) occurs from day 7 after HCT with nadirs of 3000 to 14000 platelets/μL. Pentostatin (2 mg/kg) in combination with cordycepin (2 mg/kg) is 100% effective in the T. evansi-infected mice. There is an increase in levels of some biochemical parameters, especially on liver enzymes, which are accompanied by histological lesions in the liver and kidneys. Pentostatin individually has no curative effect on infected groups.
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