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- 2025年12月05日
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4°C, sealed storage, away from moisture
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货期：1-2天
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10 mM * 1 mL/100 mg/200 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥605.0 |
|---|---|---|---|
| 规格： | 100 mg | 产品价格： | ￥550.0 |
| 规格： | 200 mg | 产品价格： | ￥1000.0 |
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AEBSF hydrochloride
CAS No. : 30827-99-7
MCE 国际站：AEBSF hydrochloride
产品活性：AEBSF hydrochloride 是丝氨酸蛋白酶 的不可逆抑制剂，可抑制例如胰凝乳蛋白酶，激肽释放酶，纤溶酶，凝血酶和胰蛋白酶。
研究领域：Metabolic Enzyme/Protease | Anti-infection
作用靶点：Thrombin | Influenza Virus | Ser/Thr Protease
In Vitro: AEBSF inhibits the constitutive production of Aβ by directly inhibiting β-secretase in five different human cell lines, both neural and nonneural.
AEBSF, as a serine protease inhibitor, inhibits the lysis of leukemic cells by human macrophages without inhibiting macrophage secretion of TNF-α and IL-1β.
AEBSF also disturbs the growth of blastocysts on endometrial cells and inhibit the adhesion of HeLa cells on HUVECs by altering the protein secretion pattern.
In Vivo: AEBSF (76.8 mg/kg daily, i.p.) results in prolongation of the survival of mice that have been given a lethal T. gondii infection.?AEBSF also reduces airway response and underlying inflammation in cockroach allergen-induced murine model.
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