- ￥188 - 3600
- MedChemExpress(MCE)
- 美国
- HY-10006
- 2025年12月05日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
4°C, sealed storage, away from moisture
- 英文名：
Alvocidib Hydrochloride; L86-8275 Hydrochloride; HMR-1275 Hydrochloride
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
131740-09-5
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg/50 mg/100 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥517.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥188.0 |
| 规格： | 5 mg | 产品价格： | ￥470.0 |
| 规格： | 10 mg | 产品价格： | ￥660.0 |
| 规格： | 25 mg | 产品价格： | ￥1386.0 |
| 规格： | 50 mg | 产品价格： | ￥2300.0 |
| 规格： | 100 mg | 产品价格： | ￥3600.0 |
MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。
Flavopiridol Hydrochloride
CAS No. : 131740-09-5
MCE 国际站：Flavopiridol Hydrochloride
产品活性：Flavopiridol Hydrochloride (Alvocidib Hydrochloride) 是一种 CDK 的广谱抑制剂，与 ATP 竞争性地抑制 CDK1，CDK2 和 CDK4 的活性，IC50 值分别为 30, 170, 100 nM。
研究领域：Cell Cycle/DNA Damage | Autophagy | Anti-infection
In Vitro: Flavopiridol (2 μM) robustly induces a distinct pattern of ER stress in CLL cells that contributes to cell death through IRE1-mediated activation of ASK1 and possibly downstream caspases. Flavopiridol results in potent upregulation of a number of PRGs in treatments lasting 4-24 h. Flavopiridol has and immediate and long-term effect on the expression of several PRGs. In serum starved cells re-stimulated with serum, flavopiridol also inhibits the expression of these genes, but subsequently, JUNB, GADD45B and EGR1 are upregulated in the presence of flavopiridol.
相关产品：Natural Product-like Compound Library | Drug Repurposing Compound Library Plus | Clinical Compound Library Plus | Bioactive Compound Library Plus | Anti-Infection Compound Library | Cell Cycle/DNA Damage Compound Library | Kinase Inhibitor Library | Anti-Cancer Compound Library | Clinical Compound Library | Antiviral Compound Library | CNS-Penetrant Compound Library | Autophagy Compound Library | Anti-Aging Compound Library | Drug Repurposing Compound Library | Endoplasmic Reticulum Stress Compound Library | Anti-Breast Cancer Compound Library | Anti-Pancreatic Cancer Compound Library | Anti-Blood Cancer Compound Library | Rare Diseases Drug Library | Anti-Prostate Cancer Compound Library | Cancer Stem Cells Compound Library | Heterocyclic Compound Library | Membrane Protein-targeted Compound Library | Cytokine Inhibitors Library | Cell Death Library | Serine/Threonine Kinase Inhibitor Library | Chloroquine | Doxorubicin hydrochloride | 5-Fluorouracil | Palbociclib | Q-VD-OPh | Abemaciclib | Valproic acid | Ro-3306 | Panobinostat | Ribociclib | Shikonin | Dinaciclib | Hydroxyurea | Probenecid | Kaempferol | Plerixafor | Dimethyl fumarate | Birinapant | Maraviroc | GSK3326595 | Baicalin | THZ1 | Flavopiridol | Ritonavir | SR-4835 | (R)-Roscovitine
热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验.08.2310.09.021.08.3210.08.022.08.4110.07.023.08.5110.06.024.08.6210.05.025.08.7410.04.026.08.9210.03.027.09.1010.02.028.0 (3)0.2mol/L醋酸盐缓冲液（pH3.6～5.6）pH0.2mol/L醋酸（ml）0.2mol/L醋酸钠（ml）3.646.33.73.844.06.04.041.09.04.236.813.24.430.519.54.625.524.54.820
/ / 900mC. 1×TE 1.00ml 100 5. 分装待转化的质粒DNA，振荡混匀。 lmg) 3-5mA. pLexA-X(0.1 B. 10mg/ml lmSperm DNA*(0.1mg) 10 * 新配制时水浴煮沸20min后，插入冰浴，保存于-20℃。 l用1×TE/LiAc重悬的酵母感受态细胞，振荡混匀。m6. 每管加入100 lm7. 各加入600 PEG/LiAc，振荡混匀，30℃恒温，250rpm振荡培养30
技术资料暂无技术资料 索取技术资料
