Mouse IL-15,Recombinant Active Protein

Mouse IL-15,Recombinant Active

Protein
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  • ¥3290
  • Abbiotec已认证
  • 美国
  • 600195
  • 2025年07月13日
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    • 详细信息
    • 技术资料
    • 保存条件

      保存于-114℃

    • 保质期

      一年

    • 英文名

      Mouse IL-15

    • 库存

      一定量库存

    • 供应商

      美国ABBIOTEC公司

    • 规格

      0.01 mg

    产品描述:
    Interleukin-15 (IL-15) is a pleiotropic pro-inflammatory cytokine that is expressed in several inflammatory disorders, including rheumatoid arthritis, psoriasis and pulmonary inflammatory diseases. IL-15 promotes activation of T cells, neutrophils and macrophages, and is critical to dendritic cell function in several model systems. Recent emerging data suggest that IL-15 may serve as a useful therapeutic target across a range of disease states. Advances in the past year highlight the beneficial effect of IL-15 neutralization in models of psoriasis and diabetes. Further evidence for IL-15 expression and effector function has emerged across a range of rheumatic disorders, including juvenile inflammatory arthritis, rheumatoid arthritis and Kawasaki disease. Interleukin-15 (IL-15) is a gamma-common cytokine, which plays an important role in the development, survival and proliferation of NK, NK T and CD8+ T cells. Recombinant Mouse IL-15 produced in E. coli is a single non-glycosylated polypeptide chain containing 115 amino acids with a MW of 13,321 Da.
    形 态 :
    Each vial contains 10 ug protein lyophilized in 10 mM sodium phosphate pH8.0. Reconstitute with 0.1 ml sterile deionized water for a final concentration of 0.1 mg/ml.
    来 源 :
    E. coli. Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.
    别 名 :
    Interleukin-15; IL-15
    纯 度 :
    Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
    分子量 :
    13321 Da
    应 用 :E, WB
    Recombinant mouse IL-15 is fully biologically active when compared to standards. The ED50, as determined by dose-dependent induction of CTLL-2 cell proliferation, is 2.5 ng/ml.
    保存条件 :
    Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.

    产品链接 :http://www.abbiotec.com/proteins/mouse-il-15

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