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- 详细信息
- 技术资料
- 保存条件:
保存于-75℃
- 保质期:
一年
- 英文名:
Human MIP-1-beta
- 库存:
一定量库存
- 供应商:
美国ABBIOTEC公司
- 规格:
0.01 mg
产品描述:
Macrophage inflammatory protein 1-beta (MIP-1-beta or C-C motif chemokine 4) is a monokine with inflammatory and chemokinetic properties. MIP-1-beta binds to CCR5, and is one of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The N-terminal processed form, MIP-1-beta (3-69) retans the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and inhibits CCR5-mediated HIV-1 entry in T-cells. MIP-1-beta (3-69) is also a ligand for CCR1 and CCR2 isoform B. Recombinant Human MIP-1 produced in E. coli is a single non-glycosylated polypeptide chain containing 69 amino acids with a MW of 7,620 Da.
形 态 :
Each vial contains 10 ug of lyophilized protein. Reconstitute with 0.1 ml sterile deionized water for a final concentration of 0.1 mg/ml.
来 源 :
E. coli. Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.
别 名 :
C-C motif chemokine 4; small-inducible cytokine A4; macrophage inflammatory protein 1-beta; MIP-1-beta; MIP-1-beta(1-69); T-cell activation protein 2; ACT-2; PAT 744; Protein H400; SIS-gamma; Lymphocyte activation gene 1 protein; Lag-1; HC21; G-26 T-lmphocyte-secreted protein; MIP-1-beta(3-69); CCL4; LAG1; MIP1B; SCYA4
纯 度 :
Purity > 98% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
分子量 :
7620 Da
应 用 :E, WB
Human MIP-1 is fully biologically active when compared to standard. The Activity is calculated by the ability to chemoattract human blood monocytes using a concentration of 2.5 - 15 ng/ml.
保存条件 :
Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
产品链接 :http://www.abbiotec.com/proteins/human-mip-1-beta
Macrophage inflammatory protein 1-beta (MIP-1-beta or C-C motif chemokine 4) is a monokine with inflammatory and chemokinetic properties. MIP-1-beta binds to CCR5, and is one of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The N-terminal processed form, MIP-1-beta (3-69) retans the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and inhibits CCR5-mediated HIV-1 entry in T-cells. MIP-1-beta (3-69) is also a ligand for CCR1 and CCR2 isoform B. Recombinant Human MIP-1 produced in E. coli is a single non-glycosylated polypeptide chain containing 69 amino acids with a MW of 7,620 Da.
形 态 :
Each vial contains 10 ug of lyophilized protein. Reconstitute with 0.1 ml sterile deionized water for a final concentration of 0.1 mg/ml.
来 源 :
E. coli. Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.
别 名 :
C-C motif chemokine 4; small-inducible cytokine A4; macrophage inflammatory protein 1-beta; MIP-1-beta; MIP-1-beta(1-69); T-cell activation protein 2; ACT-2; PAT 744; Protein H400; SIS-gamma; Lymphocyte activation gene 1 protein; Lag-1; HC21; G-26 T-lmphocyte-secreted protein; MIP-1-beta(3-69); CCL4; LAG1; MIP1B; SCYA4
纯 度 :
Purity > 98% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
分子量 :
7620 Da
应 用 :E, WB
Human MIP-1 is fully biologically active when compared to standard. The Activity is calculated by the ability to chemoattract human blood monocytes using a concentration of 2.5 - 15 ng/ml.
保存条件 :
Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
产品链接 :http://www.abbiotec.com/proteins/human-mip-1-beta
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Human MIP-1-beta,Recombinant Active Protein
¥3290






