Recombinant HumanS100 Calcium Binding Protein Z, His Tag
Synonyms Protein S100-Z, S100 calcium-binding protein Z, S100Z, Gm625, S100-zeta.
Introduction S100Z is a recently discovered member of the S100 protein family. S100 proteins are small dimeric members of the EF-hand superfamily of Ca(2+) binding proteins thought to participate in mediating intracellular Ca(2+) signals by binding to and thereby regulating target proteins in a Ca(2+)-dependent manner. S100Z is a 99-amino acid protein capable of interacting with another member of the family, S100P. There are differences in the expression level of S100Z mRNA in various tissues. The highest levels were found in spleen and leukocytes. S100Z gene expression appears to be deregulated in some tumor tissues, compared to expression in their normal counterparts.
Recombinant HumanS100 Calcium Binding Protein Z, His TagDescription S100Z Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 119 amino acids (1-99 a.a.) and having a molecular mass of 29.1 kDa. The S100Z is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Source Escherichia Coli.
Physical Appearance Sterile filtered colorless solution.
Formulation S100Z Human solution containing 20mM Tris HCL pH-8, 1mM DTT, 1mM EDTA, 50mM NaCl & 20% glycerol.
Recombinant HumanS100 Calcium Binding Protein Z, His TagStability S100Z Human although stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.
Purity Greater than 95.0% as determined by SDS-PAGE.
Amino acid sequence MGSSHHHHHH SSGLVPRGSH MPTQLEMAMD TMIRIFHRYS GKERKRFKLS KGELKLLLQR ELTEFLSCQK ETQLVDKIVQ DLDANKDNEV DFNEFVVMVA ALTVACNDYF VEQLKKKGK.
Recombinant HumanS100 Calcium Binding Protein Z, His TagUsage CHI's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.