- ￥273 - 3600
- MedChemExpress(MCE)
- 美国
- HY-N0692
- 2025年12月05日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
Gomisin-A; TJN-101; Wuweizi alcohol-B
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg/50 mg/100 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥550.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥273.0 |
| 规格： | 5 mg | 产品价格： | ￥600.0 |
| 规格： | 10 mg | 产品价格： | ￥950.0 |
| 规格： | 25 mg | 产品价格： | ￥1700.0 |
| 规格： | 50 mg | 产品价格： | ￥2550.0 |
| 规格： | 100 mg | 产品价格： | ￥3600.0 |
MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。
Schisandrol B
CAS No. : 58546-54-6
MCE 国际站：Schisandrol B
产品活性：Schisandrol B (Gomisin-A) 是 Schisandra chinensis 的主要活性成分，具有保肝作用。Schisandrol B 抑制活性氧 (ROS) 的产生。Schisandrol B 抑制 P-糖蛋白和 CYP3A 的活性，还具有抗炎，抗糖尿病和抗氧化的作用。
研究领域：Metabolic Enzyme/Protease | Immunology/Inflammation | NF-κB | Autophagy
作用靶点：Reactive Oxygen Species | Cytochrome P450 | Autophagy
In Vitro: Schisandrol B (Gomisin-A; 1-10 μM; 2 days) treatment decreases the aging related inflammatory molecules, such as, COX-2, IL1β, and TNF-α. Schisandrol B attenuates the activity of senescence-associated β-galactosidase.
Schisandrol B (Gomisin-A; 1-10 μM; 2 days) inhibits reactive oxygen species production even in the stress-induced premature senescence (SIPS)-human diploid fibroblast (HDF) cells.
Schisandrol B (Gomisin-A; 1-10 μM) inhibits the MAPK pathway and the translocation of NF-κB to the nucleus.
Schisandrol B (Gomisin-A; 1-10 μM) promotes the autophagy and mitochondrial biogenesis factors through the translocation of Nrf-2, and inhibits aging progression in the SIPS-HDF cells.
Schisandrol B (0-80 μM) dramatically alters APAP metabolic activation by inhibiting the activities of CYP2E1 and CYP3A11.
In Vivo: Schisandrol B (12.5 -200 mg/kg; oral administration; seven times with an interval of 12 hours) pretreatment significantly attenuates the increases in alanine aminotransferase and aspartate aminotransferase activity, and prevents elevated hepatic malondialdehyde formation and the depletion of GSH in a dose-dependent manner. Schisandrol B abrogates APAP-induced activation of p53 and p21, and increases expression of liver regeneration and antiapoptotic-related proteins such as cyclin D1 (CCND1), PCNA, and BCL-2.
相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Immunology/Inflammation Compound Library | Metabolism/Protease Compound Library | NF-κB Signaling Compound Library | Stem Cell Signaling Compound Library | Natural Product Library | Anti-Cancer Compound Library | Autophagy Compound Library | Anti-Aging Compound Library | Antioxidant Compound Library | Reprogramming Compound Library | Anti-diabetic Compound Library | Oxygen Sensing Compound Library | Ferroptosis Compound Library | Medicine Food Homology Compound Library | Pyroptosis Compound Library | Orally Active Compound Library | Traditional Chinese Medicine Active Compound Library | Anti-Parkinson's Disease Compound Library | Neurodegenerative Disease-related Compound Library | Mitochondria-Targeted Compound Library | Anti-Cancer Natural Product Library | Anti-inflammatory Traditional Chinese Medicine Active Compound Library | Plant-Sourced Natural Product Library | Mitochondrial Protection Compound Library | Cell Death Library | Acetylcysteine | H2DCFDA | Deferoxamine mesylate | Elesclomol | Quercetin | MitoSOX Red | L-Ascorbic acid | Mito-TEMPO | Mitoquinone mesylate | L-Glutathione reduced | Trolox | Zinc Protoporphyrin | FX-11 | Verapamil | Dimethyl fumarate | Diphenyleneiodonium chloride | Apigenin | Fenofibrate | Berberine chloride | Chlorpromazine hydrochloride | Urolithin A | TPEN | Sodium dichloroacetate | Tempol | 2-Methoxyestradiol | Ketoconazole | GSK2795039 | α-Vitamin E | 1-Aminobenzotriazole | Ciprofloxacin
热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验49e/CD29、CD49f/CD29、CD51/CD29、CD11a/CD18、CD11b/CD18、CD11c/CD18、CD41/CD61、CD51/CD61、CD49f/CD104、CD2、CD4、CD8、CD28、CD31、CD50、CD54、CD56、CD58、CD80、CD102、CD106、CD62L、CD62P、CD62E、CD15、CD15s、CD44等。 （2）B表示CD命名范围中属IGSF结构的分子，如CD79a、CD79b、CD1、CD
Crystallization of Kinesin Family Motor Proteins
nitrateShipley et al., 2004Table 2: Crystallographic parametersConstructSpace groupUnit cellResolutionStructural determinationSpecial FeatureshK349PDB: 1BG2P212121a=48.54 Åb=67.94 Åc=112.95 Å1.8 ÅMultiple isomorphous replacement rK354PDB: 2KINP212121a=71.56 Åb=73
: high-fidelity, long-range and RT-PCRs 48 3.16 Nucleic acid templates 51 3.17 Mineral oil 54 3.18 Plasticware and disposables 54 3.19 Automation of PCR and thermal cyclers 55 Protocol 3.1: Phosphorylation of the 5-end of an oligonucleotide 63
技术资料暂无技术资料 索取技术资料
