Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
CDK-activating kinases(CAKs) are multisubunit proteins that phosphorylate and thus activate certain cyclin-dependent protein kinases in the regulation of cell cycle progression. Cyclin dependent kinase7(CDK7) gene is mapped to chromosome 2p15-cen. CDK7 functions in both cyclin binding and T-loop phosphorylation and that these 2 steps of CDK1 activation are mutually dependent.
Alternate Names:
CAK;CDKN7;MO15;CAK1;STK1;p39 Mo15;KINASE SUBUNIT OF CAK;SERINE/THREONINE PROTEIN KINASE 1;CELL DIVISION PROTEIN KINASE 7;39 kDa protein kinase;CDK-activating kinase 1;Cell division protein kinase 7;Serine/threonine-protein kinase 1;TFIIH basal transcription factor complex kinase subunit.
Specificity Reaction:Hu
Application Notes:WB: 1:100-300 IHC: 1:100-500
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.