- ￥2400
- PL Laboratories
- 加拿大
- PL0402506
- 2025年07月09日
- WB: 1:100-500
- Rabbit
- Hu，Mo，Rat
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- 详细信息
- 技术资料
- 免疫原：
peptide corresponding to a sequence at the N-terminus of human MRP4.
- 亚型：
Rabbit Polyclonal IgG
- 形态：
液态
- 保存条件：
保存于-20℃
- 克隆性：
多克隆
- 标记物：
无标记（PLlabs可供应生物素、酶、荧光素标记的抗体）
- 适应物种：
Hu，Mo，Rat
- 保质期：
按说明书条件可保存1-2年
- 抗原来源：
见详细说明资料
- 目录编号：
PL0402506
- 级别：
超纯
- 库存：
大量
- 供应商：
华拓生物
- 宿主：
Rabbit
- 应用范围：
WB: 1:100-500
- 浓度：
1mg/ml
- 靶点：
ABCC4
- 抗体英文名：
ABCC4 Antibody
- 抗体名：
ABCC4抗体
- 规格：
0.1ml
ABCC4 Antibody
Cat#：PL0402506
Isotype:Rabbit Polyclonal IgG
Immunogen：peptide corresponding to a sequence at the N-terminus of human MRP4.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
ABCC4(Atp-binding cassette, subfamily c, member 4) also known as MRP4 or MOATB, is a protein that in humans is encoded by the ABCC4 gene. The ABCC4 belongs to a large family of transmembrane proteins involved in active transport of substrates out of cells. By radiation hybrid analysis, Kool et al.(1997) mapped the ABCC4 gene to chromosome 13. Using FISH, Lee et al.(1998) refined the localization to chromosome 13q32. ABCC4 acts as an independent regulator of intracellular cyclic nucleotide levels and as a mediator of cAMP-dependent signal transduction to the nucleus. The antiproliferative effect of MRP4 inhibition was related to cAMP-dependent PKA activation and CREB phosphorylation. Pharmacologic inhibition of MRP4 activity or knockdown of MRP4 via RNA interference resulted in reduced migration of DCs from human skin explants and of in vitro-generated Langerhans cells.
Alternate Names：
ABCC4 antibody;ATP binding cassette sub family C(CFTR/MRP) member 4 antibody;ATP binding cassette sub family C member 4 antibody;ATP binding cassette subfamily C member 4 antibody;ATP-binding cassette sub-family C member 4 antibody.
Specificity Reaction：Hu，Mo，Rat
Application Notes:WB: 1:100-500
Storage ：
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素（FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体，欢迎大家咨询订购。
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ABCC4抗体
￥2400
