peptide corresponding to a sequence at the C-terminus of human SMAD.
亚型:
Rabbit Polyclonal IgG
形态:
液态
保存条件:
保存于-20℃
克隆性:
多克隆
标记物:
无标记(PLlabs可供应生物素、酶、荧光素标记的抗体)
适应物种:
Hu,Mo,Rat
保质期:
按说明书条件可保存1-2年
抗原来源:
见详细说明资料
目录编号:
PL0401186
级别:
超纯
库存:
大量
供应商:
华拓生物
宿主:
Rabbit
应用范围:
WB: 1:100-500
浓度:
1mg/ml
靶点:
Smad1,2,3,5
抗体英文名:
Smad1,2,3,5 Antibody
抗体名:
Smad1,2,3,5抗体
规格:
0.1ml
Smad1,2,3,5 Antibody
Cat#:PL0401186
Isotype:Rabbit Polyclonal IgG
Immunogen:peptide corresponding to a sequence at the C-terminus of human SMAD.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
SMADs are proteins that modulate the activity of transforming growth factor beta ligands. The SMADs, often in complex with other SMADs/CoSMAD, act as transcription factors that regulate the expression of certain genes. Zhu, H et al concluded that targeted ubiquitination of SMADs may serve to control both embryonic development and a wide variety of cellular responses to TGF-beta signals. R-Smads or receptor regulated Smads are a class of proteins that include SMAD1, SMAD2, SMAD3, SMAD5, and SMAD8. In response to signals by the TGF-beta superfamily of ligands these proteins associate with receptor kinases and are phosphorylated at an SSXS motif at their extreme C-terminus.
Alternate Names:
BSP1 antibody;Dwarfin A antibody;DwfA antibody;hMAD 2 antibody;hMAD 3 antibody;hSMAD2 antibody;hSMAD3 antibody;hSmad5 antibody;JV152 antibody;JV18 antibody;JV181 antibody;JV4 1 antibody;MAD homolg 5 antibody;Mad related protein 1 antibody;MADH1 antibody;MADH2 antibody;MADH3 antibody;MADR1 antibody;MADR2 antibody;Mothers against DPP homolog 1 antibody;Sma and Mad related protein 1 antibody;SMA and MAD related protein 3 antibody;SMAD antibody;SMAD family member 1 antibody;SMAD mothers against DPP homolog 1 Drosophila antibody;Spinal muscular atrophy distal with upper limb predominance antibody;TGF beta signaling protein 1 antibody;Transforming growth factor beta signaling protein 1 antibody.
Specificity Reaction:Hu,Mo,Rat
Application Notes:WB: 1:100-500
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.