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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20℃
- 保质期:
12个月
- 英文名:
Recombinant Adrenergic Receptor Alpha 2C (ADRa2C)
- 库存:
1000
- 供应商:
上海信裕
| Organism species | Rattus norvegicus (Rat) |
| Product No. | xy977Ra01 |
| Source | Prokaryotic expression |
| Host | E.coli |
| Purity | > 95% |
| UOM | 50ug |
| Predicted Molecular Mass | n/a |
| Predicted isoelectric point | n/a |
| Applications | SDS-PAGE; WB; ELISA; IP. |
| Endotoxin Level | <1.0EU per 1µg (determined by the LAL method) |
| Subcellular Location | n/a |
| Residues | n/a |
| Formulation | Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl. |
Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37oC for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and 70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at double intensity to make location and size approximation of proteins of interest quick and easy.
肾上腺素能受体α2C(ADRα2C)重组蛋白Ready-to-use: No need to heat, dilute or add reducing agents before use.
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文献和实验到的细胞类型表达FcR,同时反应抗体含有Fc段,都应该考虑进行Fc 阻断,来确保实验的特异性,减少非特异的产生。 那么,具体哪些细胞类型需要做Fc阻断? 首先,按FcR所结合的Ig种类不同可将其分为五类,即IgG(FcγR)、IgE(FcεR)、IgA(FcαR)、IgM(FcμR)和IgD(FcδR)。 IgG类型抗体的Fc受体是FcγR,依据和Fc片段亲和力的强弱,FcγR又可以被分为三个亚家族:FcγRI(CD64)、FcγRII(CD32)和FcγRIII(CD16)以及进一步还可以分为不同
Distribution of 2A- and 2C-Adrenergic Receptor Immunoreactivity in the Central Nervous System
in the regulation of analgesia, memory, and central cardiovascular control (1 ). Three subtypes of the receptor have been identified (α2A -, α2B -, and α2C -ARs; for review, see ref. 2 ). Comparisons of the three subtypes show a high degree of sequence similarity
19的抑制剂,α-奈黄酮为CYP1A2的特异的选择性抑制剂,槲皮素为CYP2C8的特异的选择性抑制剂,磺胺苯吡唑为CYP2C9的特异的选择性抑制剂,奎尼丁为CYP2D6的特异的选择性抑制剂,酮康唑为CYP3A4/5的特异的选择性抑制剂,如选用特异的选择性抑制剂抑制不同亚型的酶的活性,便可通过化学抑制法研究药物的CYP450酶代谢表型。 3 实验方法描述 肝微粒体体外温孵法是采用肝微粒体,辅以NADPH再生系统(IPHASE汇智和源),在体外模拟生理环境条件进行代谢反应,经过一定时间的反应
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