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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Human erythrocyte Ca2++-ATPase.
- 亚型:
Mouse IgG2a
- 形态:
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
单克隆
- 标记物:
见下方详细说明
- 适应物种:
H, R, Rb, Ck
- 保质期:
1-2年
- 抗原来源:
Human erythrocyte Ca2++-ATPase.
- 目录编号:
251713
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Mouse
- 应用范围:
E, WB, IHC
- 浓度:
见详细说明信息
- 靶点:
Ca++ ATPase
- 抗体英文名:
Ca++ ATPase Antibody
- 抗体名:
Ca++ ATPase Antibody
- 规格:
0.1 mg
Ca++ ATPase Antibody产品详细介绍:
| 产品名称: | Ca++ ATPase Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 251713 |
| 规格: | 0.1 mg |
| 产品描述: | Calcium-transporting ATPase sarcoplasmic reticulum type (Ca++ ATPase) is a magnesium-dependent enzyme that catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Defects in ATP2A2 are a cause of acrokeratosis verruciformis (AKV), also known as Hopf disease. AKV is a localized disorder of keratinization, which is inherited as an autosomal dominant trait. Its onset is early in life with multiple flat-topped, flesh-colored papules on the hands and feet, punctate keratoses on the palms and soles, with varying degrees of nail involvement. |
| 克隆类型: | Mouse Monoclonal Antibody |
| 亚型: | Mouse IgG2a |
| 免疫原: | Human erythrocyte Ca2++-ATPase. |
| 适用物种: | H, R, Rb, Ck |
| 应用范围: | E, WB, IHC |
| 应用说明: | E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 别名: | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; SERCA2; SR Ca(2+)-ATPase 2; Calcium pump 2; Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform; Endoplasmic reticulum class 1/2 Ca(2+) ATPase; Ca++ ATPase; ATP2A2; ATP2B |
| 形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: |
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文献和实验Measurement of Ca2+-ATPase Activity (in PMCA and SERCA1)
and a purified enzyme, best suited for studies of Ca2+ -ATPase activity are described. The two selected membranes are the human red blood cell (RBC) ghosts, a representative of plasma membranes (PM), and the rabbit skeletal muscle SR, an intracellular membrane
能够水解ATP,并利用ATP水解释放出的能量驱动物质跨膜运输的运输蛋白称为运输ATPase, 由于它们能够进行逆浓度梯度运输, 所以有称为泵。共有四种类型的运输ATPase: ① P型离子泵(P-type ion pump),或称P型ATPase 。此类运输泵运输时需要磷酸化(P是phosphorylation的缩写),包括Na -K 泵、Ca2 离子泵。 ② V型泵(V-type pump),或称V型ATPase,主要位于小泡的膜上( V代表
Steady State ATPase Assays Coupled Enzyme System
, in Tris-HCl. Avoid using phosphate buffers for ATPase assays. 2. The coupled enzyme ATPase assay is based on the conversion of phosphoenolpyruvate (PEP) to pyruvate by pyruvate kinase (PK) coupled to the conversion
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