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- PEPROTECH
- 中国/美国
- xy-260Si01
- 2025年07月11日
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- 保存条件：
-20℃
- 保质期：
12个月
- 英文名：
Recombinant Beta-2-Microglobulin (b2M)
- 库存：
1000
- 供应商：
上海信裕
β2-微球蛋白(β2M)重组蛋白
Recombinant Beta-2-Microglobulin (b2M)
FOR IN VITRO AND RESEARCH USE ONLY, NOT FOR USE IN CLINICAL DIAGNOSTIC PROCEDURES!
| Organism species | Rhesus monkey (Simian) |
| Product No. | xy260Si01 |
| Source | Prokaryotic expression |
| Host | E.coli |
| Purity | > 95% |
| UOM | 50ug |
| Predicted Molecular Mass | n/a |
| Concentration | n/a |
| Applications | SDS-PAGE; WB; ELISA; IP. |
| Endotoxin Level | <1.0EU per 1µg (determined by the LAL method) |
β2-微球蛋白(β2M)重组蛋白
| Formulation | Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl. |
USAGE
Reconstitute in sterile PBS, pH7.2-pH7.4.
STORAGE AND STABILITY
β2-微球蛋白(β2M)重组蛋白Storage: Avoid repeated freeze/thaw cycles. Store at 2-8oC for one month. Aliquot and store at -80oC for 12 months.
Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37oC for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37oC for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
About the MARKER (complimentary)
Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and 70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at double intensity to make location and size approximation of proteins of interest quick and easy.
β2-微球蛋白(β2M)重组蛋白Ready-to-use: No need to heat, dilute or add reducing agents before use.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and 70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at double intensity to make location and size approximation of proteins of interest quick and easy.
β2-微球蛋白(β2M)重组蛋白Ready-to-use: No need to heat, dilute or add reducing agents before use.
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文献和实验相关实验
功能区: 抗原结合部位；a3功能区: CD8分子结合部位； 跨膜区 胞内区 ◆β2-微球蛋白（ β2m ）： 分子量12 kDa，由15号染色体基因编码。 肽结合槽peptide-binding cleft 抗原肽-MHC复合物（peptide-MHC, pMHC) 锚着残基（anchor residue) 两个或以上与肽结合槽相结合的氨基酸残基 口袋（pocket)大小、形状等 3. 生物学功能： （1）参与内源性抗原的递呈（诱导对病毒感染细胞和肿瘤
Ⅱ类分子提呈外源性抗原 二、MHC I类分子提呈内源性抗原 三、交叉提呈 四、CDl提呈抗原 第五章 MHC I类抗原加工的分子机制及其研究进展 第一节 引言 第二节 MHC I类分子与T细胞受体 第三节 MHC I类分子抗原加工与提呈 第四节 肽段的产生和供给 第五节 多肽装载复合物 第六节 HC和β2m二聚体的形成 第七节 肽段的装载 第八节 MHC I类分子向细胞表面的转运 第九节 结语 第六章 结构免疫学研究进展：主要组织相容性复合物的分子识别 第一
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β2-微球蛋白(β2M)重组蛋白
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