- 询价
- XAV939
- 2025年07月15日
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- 详细信息
- 技术资料
- 库存：
大量
Formula: C14H11F3N2OS
Solubility: DMSO
Purity: >99%
XAV939 is a cell-permeable small molecule inhibitor of the Wnt / β-catenin pathway that inhibits tankyrase 1 and tankyrase 2, thus stabilizing axin and stimulating β-catenin degradation.
Current research suggests that Wnt proteins act to maintain stem cells in an undifferentiated, self-renewing state. Wnt proteins act on a variety of stem cells that include neural, mammary and embryonic stem cells. In addition, XAV939 inhibits growth of DLD-1 cells, an APC-deficient colorectal cancer cell line.
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XAV939,CHIR99021,PD0325901
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