- 询价
- Cell Signaling Technology
- 3349
- USA
- 2025年11月22日
- W
- Rabbit
- H
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- 详细信息
- 技术资料
- 抗体英文名：
SGTA Antibody
- 抗原：
synthetic peptide corresponding to human SGTA
- 应用范围：
W
- 宿主：
Rabbit
- 供应商：
CST
- 级别：
详见MSDS文件
- 适应物种：
H
- 保质期：
详见说明书
- 库存：
大量
- 是否单克隆：
2
- 保存条件：
-20°c
- 规格：
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 100 ul (10 western blots) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting
Reactivity Key: H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Source |
|---|---|---|---|---|
| W | H | Endogenous | 34 | Rabbit |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | SGTA Antibody detects endogenous levels of total SGTA protein. |
| Source / Purification | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to human SGTA. Antibodies are purified by protein A and peptide affinity chromatography. Western Blotting
Western blot analysis of extracts from H1703 cells transfected with non-targeted (-) or SGTA targeted (+) siRNA. SGTA Antibody confirms the silencing of protein expression while β-Actin Antibody #4967 is used to control for loading. Western Blotting
Western blot analysis of extracts from various cell lines using SGTA Antibody. |
| Background | SGTA, small glutamine-rich tetratricopeptide repeat-containing protein A, is an ubiquitously expressed co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity (1,2). SGTA is a 34 kDa protein that is rich in glutamine residues at its C terminus and contains three tandemly repeated TPR motifs (3). The TPR domain of SGTA shows sequence similarity to the TPR domains of Hop, CHIP, and TOM70 (4). The TPR domain of SGTA also interacts with HSP90 and was recently found to be a pro-apoptotic factor (5,6).
|
| Application References | Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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