in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
形态:
Purified IgG - liquid
亚型:
Polyclonal IgG
免疫原:
Synthetic peptide corresponding to Human OAS1 – conjugated to KLH.
规格:
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Rabbit anti Human LOX-1 antibody recognizes the extracellular (C-terminal) domain of human LOX-1, a receptor for oxidised low-density lipoproteins (LDL). This receptor mediates the recognition, internalisation and degradation of oxidised LDL. It is a Type II membrane protein with a typical C-type lectin structure at the extracellular C-terminus which recognises the ligand. LOX-1 activation by oxidised LDL causes endothelial changes such as decreased nitric oxide release and an increased expression of adhesion molecules. LOX-1 also binds activated platelets and apoptotic cells. The expression of LOX-1 is induced by proatherogenic conditions such as hyperlipidemia, hypertension and diabetes and as such appears to contribute to the pathogenesis of vascular disorders, particularly atherosclerosis. http://www.creative-diagnostics.com/Anti-OAS1-Pab-236752-147.htm