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- 详细信息
- 文献和实验
- 技术资料
- 形态:
液态/粉状
- 保存条件:
-20℃保存
- 克隆性:
多克隆
- 标记物:
见说明书
- 适应物种:
人,大鼠,小鼠,兔
- 宿主:
Goat,Rabbit,Mouse
- 应用范围:
科研使用
- 浓度:
1mg/1ml
- 靶点:
来电咨询
- Neuroendocrine (Chromogranin A) Monoclonal Antibody保存于运输说明:
- Store at -20°C
- 详细信息:
-
Description 
Monoclonal Antibody against Neuroendocrine (Chromogranin A) Clone 
PHE5 Form 
Affinity Purified Antibody Host 
Mouse Species Reactivity 
Human IsoType 
IgG1 [Ab] 
Neuroendocrine (Chromogranin A) Monoclonal AntibodyAntibody is supplied in PBS containing 1% BSA and 0.1% sodium azide Specificity 
PHE5 is specific to chromogranin A, a highly acidic protein associated with the "dense core" granules of many cells of the neural and neuroendocrine system. It reacts with neuroendocrine cells of the gut, pancreatic islet and adrenal medulla, but does not react with any cells in the brain or with melanoma cells. The antibody stains carcinoid tumors, pheochromocytomas and paragangliomas. It is nonreactive with carcinomas, lymphomas and sarcomas. Uses 
This antibody can be used for staining of paraffin-embedded tissue sections fixed in neutral buffered formalin and is compatible with most commonly used histological fixatives. Choose a good quality enzyme-linked anti-mouse IgG1 antibody for detection. Suggested Working Dilution 
The optimal working dilution should be determined for each specific assay condition. This antibody is sold for laboratory research use only, not for human or in-vivo use. Covance antibodies may not be resold or modified for resale without prior written approval. - Immunohistopathology: 1:50
Notes 
This antibody is distributed by arrangement with Enzo Biochem Corporation.
Storage 
Neuroendocrine (Chromogranin A) Monoclonal AntibodyStore at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody. Long term storage should be at -80°C. This shelf-life of this product is approximately 1 year. References 
Papotti M, Macri L, Finzi G, Capella C, Eusebi V, Bussolati G. Neuroendocrine differentiation in carcinomas of the breast: a study of 51 cases. Sem. in Diag. Path. 6:174-188, 1989.
Lloyd RV, Cano M, Rosa P, Hille A, Huttner WB. Distribution of Chromogranin A and Secretogranin I (Chromogranin B) in Neuroendocrine Cells and Tumors. Am. J. Pathol. 130:296-304, 1988.
Bordi C, Pilato EP, D¡¯Adda T. Comparative study of seven neuroendocrine markers in pancreatic endocrine tumours. Virchows Archiv. A. Path. Anat. 413:387-398, 1988.
Riddell K, Tippens D, Gown, AM. PHE5, a new monoclonal antibody to a unique neuroendocrine granule protein. Lab. Invest. 56.:64A, 1987.
Warranty/Conditions 
Covance products may not be resold or modified for resale without prior written approval. - Neuroendocrine (Chromogranin A) Monoclonal Antibody
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