- 询价
- R&D
- 美国/中国
- xy-39416
- 2025年07月16日
- 科研使用
- Goat，Rabbit，Mouse
- 人，大鼠，小鼠，兔
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- 详细信息
- 文献和实验
- 技术资料
- 形态：
液态/粉状
- 保存条件：
-20℃保存
- 克隆性：
多克隆
- 标记物：
见说明书
- 适应物种：
人，大鼠，小鼠，兔
- 宿主：
Goat，Rabbit，Mouse
- 应用范围：
科研使用
- 浓度：
1mg/1ml
- 靶点：
来电咨询
- Tau (Tau 12) Monoclonal Antibody, Purified (SIGNET)详细信息：
-
Description 
Purified Monoclonal Antibody against Human Tau
(Formerly Signet Catalog Nos: 9416-02, 9416-05, 9416-10)Intended Use **Research Use Only (RUO)**
This product is sold for laboratory research use only, not for human or in-vivo use.Clone Tau 12 Form Purified Antibody (in PBS; no preservatives or carrier proteins) Host Mouse Species Reactivity Tau (Tau 12) Monoclonal Antibody, Purified (SIGNET)Human IsoType IgG1 [Ab] 0.5 mg/mL Specificity This antibody is specific for an epitope that lies between amino acids 9-18 of human Tau. Uses This antibody is effective in immunoblotting, immunohistochemistry (IHC) and ELISA. Suggested Working Dilution The optimal working dilution should be determined for each specific assay condition. Storage Tau (Tau 12) Monoclonal Antibody, Purified (SIGNET)Do not store antibody diluted below 50 ug/mL in the absence of protein (i.e.: add 2% bovine serum albumin). The antibody is best stored undiluted at -80°C. It is suggested that the total volume is aliquoted upon initial thaw. References Guillozet-Bongaarts AL, Garcia-Sierra F, Reynolds MR, Horowitz PM, Fu Y, Wang T, Cahill ME, Bigio EH, Berry RW, Binder LI. Tau truncation during neurofibrillary tangle evolution in Alzheimer ’s disease. Neurobiol Aging 26(7):1015-22, 2005.
Horowitz PM, Patterson KR, Guillozet-Bongaarts AL, Reynolds MR, Carroll CA, Weintraub ST, Bennett DA, Cryns VL, Berry RW, Binder LI. Early N terminal changes and caspase-6 cleavage of tau in Alzheimers disease. J Neurosci 24(36):7895-902, 2004.
Garcia-Sierra F, Ghoshal N, Quinn B, Berry RW, Binder LI. Conformational changes and truncation of tau protein during tangle evolution in Alzheimers disease. J Alzheimers Dis 5(2):65-77, 2003.Warranty/Conditions Covance products may not be resold or modified for resale without prior written approval. - Tau (Tau 12) Monoclonal Antibody, Purified (SIGNET)
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文献和实验Characterization and Use of Monoclonal Antibodies to Tau and Paired Helical FilamentTau
of the available antibodies have been produced with preparations obtained from the brains of patients with AD, although a few antibodies have been generated with tau purified from bovine brain. This chapter restricts discussion to the production
ml 标准品 （Standards ） ： 1.2ng/瓶 2 瓶 底物工作液（TMB Solution ） 12ml 第一抗体工作液（ Biotinylated Antibody ） 12ml
ml 标准品 （Standards ） ： 1.2ng/瓶 2 瓶 底物工作液（TMB Solution ） 12ml 第一抗体工作液（ Biotinylated Antibody ） 12ml
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