Cytokeratin-8 Monoclonal Antibody, Purified

Cytokeratin-8 Monoclonal Antib

ody, Purified
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  • 询价
  • R&D
  • 美国/中国
  • xy-162P
  • 2025年07月12日
  • 科研使用
  • Goat,Rabbit,Mouse
  • 人,大鼠,小鼠,兔
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    点击 QQ 联系

    • 详细信息
    • 技术资料
    • 形态

      液态/粉状

    • 保存条件

      -20℃保存

    • 克隆性

      多克隆

    • 标记物

      见说明书

    • 适应物种

      人,大鼠,小鼠,兔

    • 宿主

      Goat,Rabbit,Mouse

    • 应用范围

      科研使用

    • 浓度

      1mg/1ml

    • 靶点

      来电咨询

    • Cytokeratin-8 Monoclonal Antibody, Purified详细信息:
    • Description Cytokeratin-8 Monoclonal Antibody, Purified - STRUCTURAL PROTEINS & CELL COMPONENTS Monoclonal Antibody against Cytokeratin-8 (K-8)
      Intended Use Cytokeratin-8 Monoclonal Antib ** In Vitro Diagnostic (IVD) **
      Clone Cytokeratin-8 Monoclonal Antib 1E8
      Form Cytokeratin-8 Monoclonal Antib Purified Antibody (Stored in PBS + 0.03% Thimerosal)
      Host Cytokeratin-8 Monoclonal Antib Mouse
      Species Reactivity Cytokeratin-8 Monoclonal Antib Human
      IsoType Cytokeratin-8 Monoclonal Antib Cytokeratin-8 Monoclonal Antibody, Purified IgG2a
      Specificity Cytokeratin-8 Monoclonal Antibody, Purified - STRUCTURAL PROTEINS & CELL COMPONENTS Cytokeratin-8 copolymerizes with cytokeratin-18 to form a component of the cytoskeleton in simple epithelia and many epithelial cell derived cancers. Antibody 1E8 was raised against the 12 carboxy-terminal amino acids of HK-8 preceded by a cysteine, CKLVSESSDVLPK. This antibody recognizes human cytokeratin-8.
      Uses Cytokeratin-8 Monoclonal Antibody, Purified - STRUCTURAL PROTEINS & CELL COMPONENTS This antibody is effective in immunoblotting (WB), immunofluorescence (IF) and immunohistochemistry (IHC).
      Suggested Working Dilution Cytokeratin-8 Monoclonal Antibody, Purified - STRUCTURAL PROTEINS & CELL COMPONENTS The optimal working dilution should be determined for each specific assay condition.
      • WB: 1:1,000*
      • IF: 1:1,000
      • IHC: 1:1,000 with either biotin based detection systems such as USA Ultra Streptavidin Detection (SIG-32250) or polymer based detection systems such as ACUITYAdvanced Biotin Free Polymer Detection (SIG-32902).
        Tissue Sections: Paraffin-embedded tissues
        Pretreatment: For optimal staining, the sections should be pretreated with an antigen unmasking solution such as Citrate Buffer Retrieval solution (SIG-31932, SIG-31934).
        Incubation: 60 minutes at room temperature
      Notes Cytokeratin-8 Monoclonal Antibody, Purified - STRUCTURAL PROTEINS & CELL COMPONENTS *Predicted MW = 54 kDa
      Storage Cytokeratin-8 Monoclonal Antibody, Purified - STRUCTURAL PROTEINS & CELL COMPONENTS Cytokeratin-8 Monoclonal Antibody, Purified When stored at ≤20°C, product is stable until the date shown on the label. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody. If thawed and stored at 2-8°C, product is stable for 24 months from the date of thaw or until the expiry date on the label, whichever comes first.
      References Cytokeratin-8 Monoclonal Antib Hembrough TA, Li L, Gonias SL. Cell surface cytokeratin-8 is the major plasminogen receptor on breast cancer cells and is required for the accelerated activation of cell-associated plasminogen by tissue-type plasminogen activator. J Biol Chem 271:25684-25691, 1996. [WB, IF]
      Warranty/Conditions Cytokeratin-8 Monoclonal Antibody, Purified - STRUCTURAL PROTEINS & CELL COMPONENTS Covance products may not be resold or modified for resale without prior written approval.
    • Cytokeratin-8 Monoclonal Antibody, Purified
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      xy-0296R-xyy3 Rabbit Anti-mouse IgG/Cy3Cy3标记的兔抗小鼠IgG

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