- ￥548 - 5460
- MedChemExpress(MCE)
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- HY-N0069
- 2025年12月05日
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- 详细信息
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
Solamargin; δ-Solanigrine
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
20311-51-7
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg/50 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥1719.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥548.0 |
| 规格： | 5 mg | 产品价格： | ￥1200.0 |
| 规格： | 10 mg | 产品价格： | ￥1800.0 |
| 规格： | 25 mg | 产品价格： | ￥3700.0 |
| 规格： | 50 mg | 产品价格： | ￥5460.0 |
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Solamargine
CAS No. : 20311-51-7
MCE 国际站：Solamargine
产品活性：Solamargine 是一种来源于茄属植物的类固醇 Solasodine 的衍生物，在多种癌症中均表现出抗癌活性。Solamargine 诱导非选择性细胞毒性和 P-gp 抑制作用。Solamargine 通过下调 MMP-2 和 MMP-9 的表达和活性来显着抑制 HepG2 细胞的迁移和侵袭。
研究领域：Membrane Transporter/Ion Channel | Apoptosis
作用靶点：P-glycoprotein | Apoptosis
In Vitro: Solamargine (15 μg/ml; 72 hours) predominantly stimulates the cells of the G2/M phase to apoptosis.
Solamargine (72 hours) dramatically inhibits the proliferation of SMMC-7721 and HepG2 cells in a dose- and time-dependent manner. The IC50s are 9.21 and 19.88 μg/ml, respectively.
In Vivo: Solamargine (10 mg/kg; intragastric administration; once daily for 8 days) exhibits an antitumor effect and promotes the apoptosis of GC in vivo.
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