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Human 4-1BB(CJ38)

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  • SinoBio
  • 国产
  • CJ38
  • 2025年11月05日
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    上海经科化学科技有限公司
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件：

      蛋白表达区间:Leu24-Gln186

    • 保质期：

      See instructions

    • 英文名：

      标签:C-Fc-6His

    • 库存：

      表达系统:Human Cells

    • 供应商：

      上海经科化学科技有限公司

    • 规格：

      10ug/50ug/500ug/1mg

    规格：10ug产品价格：￥800.0
    规格：50ug产品价格：￥1680.0
    规格：500ug产品价格：￥10400.0
    规格：1mg产品价格：￥16800.0
    产品描述
    Recombinant Human 4-1BB Ligand Receptor is produced by our Mammalian expression system and the target gene encoding Leu24-Gln186 is expressed with a human IgG1 Fc, 6His tag at the C-terminus.
    蛋白编号
    Q07011
    产品别称
    CD137; ILA; TNFRSF9; 4-1BB ligand receptor; CDw137; T-cell antigen 4-1BB homolog; T-cell antigen ILA
    偶联
    Unconjugated
    分子量
    44 KDa
    表观分子量
    55-75 KDa, reducing conditions
    剂型描述
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    内毒素
    < 1 EU/µg as determined by LAL test.
    生物活性-BLI
    Loaded Human 4-1BB-Fc-His(Cat#CJ38) on HIS1K Biosensor, can bind Anti-Human CD137 mAb(Cat#NC046) with an affinity constant of 12.2 nM as determined in BLI assay. (Regularly tested)
    生物活性-ELISA
    Immobilized Human 4-1BB-Fc-His(Cat#CJ38) at 2μg/ml (100 μl/well)can bind Anti-Human CD137 mAb(Cat#NC046).The ED50 of Anti-Human CD137 mAb(Cat#NC046) is 0.41ug/ml. (Regularly tested)
    复溶
    • Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
    • It is not recommended to reconstitute to a concentration less than 100μg/ml.
    • Dissolve the lyophilized protein in distilled water.
    • Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
    运输条件
    • The product is shipped at ambient temperature.
    • Upon receipt, store it immediately at the temperature listed below.
    保存条件
    • Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
    • Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
    • Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    产品背景
    Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells, but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL, and possibly active during T cell activation.

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    图标文献和实验
    该产品被引用文献

    Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells, but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL, and possibly active during T cell activation.

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    文献支持
    Human 4-1BB(CJ38)
    ￥800 - 16800