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蛋白表达区间:Gln607-Asn686&Trp795-Leu888
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- 英文名:
标签:N-6His
- 库存:
表达系统:E.coli
- 供应商:
上海经科化学科技有限公司
- 规格:
10ug/50ug/500ug/1mg
| 规格: | 10ug | 产品价格: | ¥1200.0 |
|---|---|---|---|
| 规格: | 50ug | 产品价格: | ¥3520.0 |
| 规格: | 500ug | 产品价格: | ¥12320.0 |
| 规格: | 1mg | 产品价格: | ¥19200.0 |
- The product is shipped on dry ice/polar packs.
- Upon receipt, store it immediately at the temperature listed below.
- Store at ≤-70°C, stable for 6 months after receipt.
- Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
- Please minimize freeze-thaw cycles.
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文献和实验Receptor-type tyrosine-protein phosphatase-like N (PTPRN) belongs to the protein-tyrosine phosphatase family and receptor class 8 subfamily. PTPRN contains 1 tyrosine-protein phosphatase domain, is expressed in neuroendocrine cells only. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. It implicated in neuroendocrine secretory processes. It may be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. It seems to lack intrinsic enzyme activity, may play a role in the regulation of secretory granules via its interaction with SNTB2. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus.
Expression, Purification, and Characterization of Engineered Antibody CH2 and VH Domains
scaffolds of much smaller size and high stability. Immunoglobulin-based scaffolds including Fab (∼50 kD), ScFv (∼30 kD), and VH domain (termed domain antibody, dAb) (∼15 kD) have been well established. Recently, a new scaffold based on human IgG1 CH2 domain
Isolation and Culture of Human Osteoblasts
; these cells cover most of the bone surfaces in mature bone. (4 ) Preosteoblast-a fibroblastic proliferative cell with osteogenic capacity. In addition, bone contains cells of a distinct lineage, the osteoclast (reviewed in Ch. 4).
Human Antibodies by Guided Selection
. This chapter will describe the sequential guided selection procedure using a Fab format as an example. The first step is to clone the variable regions of a mouse antibody to a phagemid vector containing human constant domains, C? and CH1, which results
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