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Human Serpin A12(C192)

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  • ¥840 - 14080
  • SinoBio
  • 国产
  • C192
  • 2026年04月18日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      蛋白表达区间:Leu21-Lys414

    • 保质期

      See instructions

    • 英文名

      标签:N-GST

    • 库存

      表达系统:E.coli

    • 供应商

      上海经科化学科技有限公司

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥840.0
    规格:50ug产品价格:¥2520.0
    规格:500ug产品价格:¥9840.0
    规格:1mg产品价格:¥14080.0
    产品描述
    Recombinant Human Serine Protease Inhibitor-clade A12 is produced by our E.coli expression system and the target gene encoding Leu21-Lys414 is expressed with a GST tag at the N-terminus.
    蛋白编号
    Q8IW75
    产品别称
    Serpin A12; OL-64; Visceral Adipose Tissue-Derived Serine Protease Inhibitor; Vaspin; Visceral Adipose-Specific Serpin; SERPINA12
    偶联
    Unconjugated
    分子量
    71.4 KDa
    表观分子量
    72 KDa, reducing conditions
    剂型描述
    Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, 160mM NaCl, 0.2mM PMSF, 1mM DTT, 10% Glycerine, pH 7.2.
    内毒素
    < 1 EU/µg as determined by LAL test.
    纯度-SDS-PAGE
    Greater than 80% as determined by reducing SDS-PAGE. (QC verified)
    运输条件
    • The product is shipped on dry ice/polar packs.
    • Upon receipt, store it immediately at the temperature listed below.
    保存条件
    • Store at ≤-70°C, stable for 6 months after receipt.
    • Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
    • Please minimize freeze-thaw cycles.
    产品背景
    Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin has three β-sheets, nine α-helices, and one central loop; the structure is part of the set of distinctive features that are descriptive of Serpin family members. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. A recent publication indicates that Vaspin mRNA expression in visceral fat is positively correlated with BMI and percent of body fat. and could be associated with parameters of obesity, insulin resistance, and glucose metabolism. These findings suggest a potential clinical use for Vaspin in ameliorating certain aberrations seen in the obesity metabolic syndrome.

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    图标文献和实验
    该产品被引用文献

    Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin has three β-sheets, nine α-helices, and one central loop; the structure is part of the set of distinctive features that are descriptive of Serpin family members. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. A recent publication indicates that Vaspin mRNA expression in visceral fat is positively correlated with BMI and percent of body fat. and could be associated with parameters of obesity, insulin resistance, and glucose metabolism. These findings suggest a potential clinical use for Vaspin in ameliorating certain aberrations seen in the obesity metabolic syndrome.

    相关实验
    • Mutational Analysis in Antithrombin Deficiency

      Human antithrombin is a single-chain glycoprotein of MW 58 kDa and the most important plasma inhibitor of the coagulation serine proteases. It is a member of the serine protease inhibitor (SERPIN) family of proteins and in common

    • 请大家给我看看这对引物是不是有问题

      : >gi|219566|dbj|D12525.1|HUMCYP1A12 Homo sapiens gene for cytochrome P450IA1, 3'flanking region Length = 650 Score = 44.1 bits (22), Expect = 0.013 Identities = 22/22 (100%) Strand = Plus / Minus Query: 21 ttaggagtcttgtctcatgcct 42

    • 蛋白复性(三)-蛋白质的结构转换

      摘要  许多不相关的蛋白质含有相同的短肽序列却形成不同的空间构象. 结构转换广泛存在于蛋白质折叠和功能过程中, 具有重要的生物学意义. 综述了Serpin和EF-Tu的失活、血细胞凝集素的激活、蛋白酶成熟、亚基装配和蛋白质淀粉样化等过程中肽链同源肽段的结构转换模式, 并讨论了它在理解蛋白质折叠机理和“构象病”病因中的应用. 关键词  蛋白质折叠, 结构转换, α/β转换, 淀粉样化   蛋白质的空间结构是体现生物功能的基础, 蛋白质折叠则是形成

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    文献支持
    Human Serpin A12(C192)
    ¥840 - 14080