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- 保存条件:
蛋白表达区间:Lys28-Ala214
- 保质期:
See instructions
- 英文名:
标签:C-6His
- 库存:
表达系统:Human Cells
- 供应商:
上海经科化学科技有限公司
- 规格:
10ug/50ug/500ug/1mg
| 规格: | 10ug | 产品价格: | ¥1200.0 |
|---|---|---|---|
| 规格: | 50ug | 产品价格: | ¥3520.0 |
| 规格: | 500ug | 产品价格: | ¥13440.0 |
| 规格: | 1mg | 产品价格: | ¥19200.0 |
- Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
- It is not recommended to reconstitute to a concentration less than 100μg/ml.
- Dissolve the lyophilized protein in distilled water.
- Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- The product is shipped at ambient temperature.
- Upon receipt, store it immediately at the temperature listed below.
- Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
- Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
- Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
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文献和实验OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation by CD40-CD40 Ligand and CD28-B7. The interaction between OX40 and OX40 ligand (OX40L) will occur when activated T cells bind to professional antigen-presenting cells (APCs). The T-cell functions, including cytokine production, expansion, and survival, are then enhanced by the OX40 costimulatory signals. OX40 signals are critical for controlling the function and differentiation of Foxp3+ regulatory T cells. OX40-OX40L interaction regulates T-cell tolerance, peripheral T-cell homeostasis, and T-cell-mediated inflammatory diseases.
xxzjcg 急求OX40基因序列,在gene bank 里没有明确的OX40基因序列 woxingwosu 根据你的基因,我查了一下NCBI,上面有多个OX40(http://www.ncbi.nlm.nih.gov/gene?term=OX40),我列举了其中一个,TNFRSF4 tumor necrosis factor receptor superfamily, member 4 [ Homo sapiens
人OX40 Ligand(OX40L)ELISA试剂盒 说明书
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 人OX40 Ligand ( OX40L )ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗人 OX40L/TNFSF4 单抗包被于酶标板上,标准品和样品中的 OX40L与单抗结合,加入
「少吃」真的可以帮助杀死癌细胞!模拟禁食可重塑机体免疫,提高癌症免疫治疗的效果
免疫反应,并可减少其副作用。 禁食模拟饮食可以作用于肿瘤微环境,增加了低免疫原性的三阴性乳腺肿瘤(TNBC)中免疫治疗(抗 PD-L1 和抗 OX40)的效果。此外,FMD 还可以通过阻止免疫反应的过度激活,减少免疫相关不良事件(irAEs)的发生。 图片来源:Cell Reports 主要研究内容 禁食模拟饮食联合抗 OX40/抗 PD-L1 可阻止乳腺癌的进展 首先,研究人员将 4T1 乳腺癌细胞原位植入小鼠乳腺脂肪垫,然后用抗 OX40/抗 PD-L1 单独或联合治疗,并设置禁食模拟饮食
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