产品封面图
文献支持

Human IDE

收藏
  • ¥1200 - 17600
  • SinoBio
  • 国产
  • CA05
  • 2025年12月26日
    avatar
  • 企业认证

    点击 QQ 联系

  • 万千商家帮你免费找货

    0 人在求购买到急需产品
    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      蛋白表达区间:Met42-Leu1019

    • 保质期

      See instructions

    • 英文名

      标签:C-6His

    • 库存

      表达系统:Human Cells

    • 供应商

      上海经科化学科技有限公司

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥1200.0
    规格:50ug产品价格:¥3520.0
    规格:500ug产品价格:¥12320.0
    规格:1mg产品价格:¥17600.0
    产品描述
    Recombinant Human Insulin-Degrading Enzyme is produced by our Mammalian expression system and the target gene encoding Met42-Leu1019 is expressed with a 6His tag at the C-terminus.
    蛋白编号
    P14735
    产品别称
    Insulin-Degrading Enzyme; Abeta-Degrading Protease; Insulin Protease; Insulinase; Insulysin; IDE
    偶联
    Unconjugated
    分子量
    114.25 KDa
    表观分子量
    120 KDa, reducing conditions
    剂型描述
    Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 0.05% Brij35, 10% Glycerol, pH 7.5.
    内毒素
    < 1 EU/µg as determined by LAL test.
    纯度-SDS-PAGE
    Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
    运输条件
    • The product is shipped on dry ice/polar packs.
    • Upon receipt, store it immediately at the temperature listed below.
    保存条件
    • Store at ≤-70°C, stable for 6 months after receipt.
    • Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
    • Please minimize freeze-thaw cycles.
    产品背景
    Insulin-Degrading Enzyme (IDE) is a secreted enzyme that belongs to the peptidase M16 family. IDE is a large zinc-binding protease and cleaves multiple short polypeptides that vary considerably in sequence. IDE plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin, and other peptides, and thereby plays a role in intercellular peptide signaling. IDE degrades amyloid formed by APP and IAPP. IDE may participate in the degradation and clearance of naturally secreted amyloid β-protein by neurons and microglia. IDE, which migrates at 110 kDa during gel electrophoresis under denaturing conditions, has since been shown to have additional substrates, including the signaling peptides glucagon, TGF α and β-endorphin.

    风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标文献和实验
    该产品被引用文献

    Insulin-Degrading Enzyme (IDE) is a secreted enzyme that belongs to the peptidase M16 family. IDE is a large zinc-binding protease and cleaves multiple short polypeptides that vary considerably in sequence. IDE plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin, and other peptides, and thereby plays a role in intercellular peptide signaling. IDE degrades amyloid formed by APP and IAPP. IDE may participate in the degradation and clearance of naturally secreted amyloid β-protein by neurons and microglia. IDE, which migrates at 110 kDa during gel electrophoresis under denaturing conditions, has since been shown to have additional substrates, including the signaling peptides glucagon, TGF α and β-endorphin.

    相关实验
    • 血管活性肠肽 vasoactive intestinal pept-ide

        血管活性肠肽 vasoactive intestinal pept- ide 缩写 VIP.为从小肠粘膜提取的一种直链肽.由 28个氨基酸残基组成.其排列为一部分胰高血糖素( glucagon)和催胰液素( secretin).具有可使血管舒张降低血压的作用,从肝动脉开始,对内脏血管具有较强的作用能力,但对股动脉则全无作用。对肠液的分泌具有很强的促进作用.但对胰腺的分泌其促进作用很弱,对胃液的分泌可起抑制作用;对消化道平滑肌的收缩产生抑制作用。对血糖的增高作用较弱.在生理

    • Human Neuritin说明书

      人 Neuritin 酶联免疫分析(ELISA) 试剂盒使用说明书 本试剂仅供研究使用         目的:本试剂盒用于测定人血清,血浆及相关液体样本 中Neuritin 的含量。 实验原理:    本试剂盒应用双抗体夹心法测定标本中人 Neuritin 水平。用纯化的 Neuritin 抗体 包被微孔板,制成固相抗体,往包被单抗的微孔中加入 Neuritin ,再与 HRP 标记的 Neuritin 抗体结合,形成抗体

    • 【下载】图书:Human Genetics: Concepts and Applications

      Human Genetics: Concepts and Applications(5th edition) Amazon网站介绍: http://www.amazon.com/Human-Genetics-Applications-Ricki-Lewis/dp/007246268X Author: Ricki Lewis ISBN: 007246268X Publisher: McGraw-Hill, 2002 Format: PDF - 440 pages Size: 79

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    ¥1960
    上海羽哚生物科技有限公司
    2025年07月11日询价
    ¥1960
    武汉琼格生物科技有限公司
    2025年06月28日询价
    询价
    维百奥(北京)生物科技有限公司
    2025年12月23日询价
    ¥1268
    普健生物(武汉)科技有限公司
    2025年07月12日询价
    ¥1880
    武汉佰乐博生物技术有限公司
    2025年07月13日询价
    文献支持
    Human IDE
    ¥1200 - 17600