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Human IFN gamma(C014)

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  • ¥240 - 3600
  • SinoBio
  • 国产
  • C014
  • 2025年11月08日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      蛋白表达区间:Gln24-Gln166

    • 保质期

      See instructions

    • 英文名

      标签:Tag free

    • 库存

      表达系统:E.coli

    • 供应商

      上海经科化学科技有限公司

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥240.0
    规格:50ug产品价格:¥800.0
    规格:500ug产品价格:¥2520.0
    规格:1mg产品价格:¥3600.0
    产品描述
    Recombinant Human Interferon Gamma is produced by our E.coli expression system and the target gene encoding Gln24-Gln166 is expressed.
     
    蛋白编号
    P01579
     
    产品别称
    Interferon Gamma; IFN-Gamma; Immune Interferon; IFNG
     
    分子量
    16.88 KDa
     
    表观分子量
    16 KDa, reducing conditions
     
    剂型描述
    Lyophilized from a 0.2 μm filtered solution of 20mM PB, 5% Sucrose, 4% Mannitol, 0.02% Tween 80, pH7.4.
     
    内毒素
    < 0.01 EU/µg as determined by LAL test.
     
    纯度-SDS-PAGE
    Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
     
    纯度-SEC-HPLC
    Greater than 95% as determined by SEC-HPLC. (Regularly tested)
     
    生物活性-Cell Based Assay
    Measured by a cytotoxicity assay using HT-29 cells. The ED50 for this effect is 17 pg/ml. (Regularly tested)
     
    复溶
    • Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
    • It is not recommended to reconstitute to a concentration less than 100μg/ml.
    • Dissolve the lyophilized protein in distilled water.
    • Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
     
    运输条件
    • The product is shipped at ambient temperature.
    • Upon receipt, store it immediately at the temperature listed below.
     
    保存条件
    • Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
    • Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
    • Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
     
    产品背景
    IFNγ is the major interferon produced by mitogenically or antigenically stimulated lymphocytes. It is structurally different from type I interferon and its major activity is immunoregulation. It has been implicated in the expression of class II histocompatibility antigens in cells that do not normally produce them, leading to autoimmune disease. Interferon gamma is produced mainly byT-cells and natural killer cells activated by antigens, mitogens, or alloantigens. It is produced by lymphocytes expressing the surface antigens CD4 and CD8. IFNγ synthesis is induced by IL-2, FGF-basic, and EGF.

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    图标文献和实验
    该产品被引用文献

    IFNγ is the major interferon produced by mitogenically or antigenically stimulated lymphocytes. It is structurally different from type I interferon and its major activity is immunoregulation. It has been implicated in the expression of class II histocompatibility antigens in cells that do not normally produce them, leading to autoimmune disease. Interferon gamma is produced mainly byT-cells and natural killer cells activated by antigens, mitogens, or alloantigens. It is produced by lymphocytes expressing the surface antigens CD4 and CD8. IFNγ synthesis is induced by IL-2, FGF-basic, and EGF.

    相关实验
    • Mutational Analysis of the Human Protein C Gene

      The single gene for protein C is located at position q13–q14 on chromosome 2 (1 ). Two groups have described human genomic clones of protein C isolated from phage l charon libraries using cDNA for human protein C as hybridization probes

    • In Vitro Stimulation and Detection of IFN Production in Human Plasmacytoid Dendritic Cells

      Type-1 interferons (IFNs), including IFNα/β, are a family of cytokines produced rapidly upon pathogen encounter and crucial for bridging innate and adaptive immunity. IFNα has been widely appreciated as a multifunctional cytokine involved

    • 干扰素(IFN

      、DNA或RNA病毒、多聚肌苷酸多聚胞苷酸(Poly I-C)、多核苷酸等刺激物诱导下产生。IFN-α/β在pH2或pH11以及热(56℃)条件下仍稳定,而IFN-γ则很易丧失活性。 2.IFN-α/β的分子结构和基因 IFN-α和IFN-β基因均位于人9号染色体和小鼠4号染色体,并连锁在一起。IFN-α基因至少有20个,成串排列在一个区域,无内含子,同一种属IFN-α不同基因产物其氨基酸同原性≥80%。人和小鼠IFN-β基因只有一个,无内含子,与IFN-α基因连锁在一起。IFN-β与IFN

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    文献支持
    Human IFN gamma(C014)
    ¥240 - 3600