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Human FGF-12

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  • ¥640 - 17600
  • SinoBio
  • 国产
  • C222
  • 2025年11月09日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      蛋白表达区间:Met1-Thr181

    • 保质期

      See instructions

    • 英文名

      标签:Tag free

    • 库存

      表达系统:E.coli

    • 供应商

      上海经科化学科技有限公司

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥640.0
    规格:50ug产品价格:¥1760.0
    规格:500ug产品价格:¥12320.0
    规格:1mg产品价格:¥17600.0
    产品描述
    Recombinant Human Fibroblast Growth Factor 12 is produced by our E.coli expression system and the target gene encoding Met1-Thr181 is expressed.
     
    蛋白编号
    P61328-2
     
    产品别称
    Fibroblast Growth Factor 12; FGF-12; Fibroblast Growth Factor Homologous Factor 1; FHF-1; Myocyte-Activating Factor; FGF12; FGF12B; FHF1
     
    分子量
    20.45 KDa
     
    观分子量
    19 KDa, reducing conditions
     
    剂型描述
    Lyophilized from a 0.2 μm filtered solution of PBS, 5mM EDTA, pH 7.5.
     
    内毒素
    < 1 EU/µg as determined by LAL test.
     
    纯度-SDS-PAGE
    Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
     
    复溶
    • Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
    • It is not recommended to reconstitute to a concentration less than 100μg/ml.
    • Dissolve the lyophilized protein in distilled water.
    • Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
     
    运输条件
    • The product is shipped at ambient temperature.
    • Upon receipt, store it immediately at the temperature listed below.
     
    保存条件
    • Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
    • Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
    • Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
     
    产品背景
    Fibroblast Growth Factor 12 (FGF-12) is a member of the fibroblast growth factor (FGF) family. FGF-12 is probably involved in nervous system development and function. FGF-12 lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfectedinto mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.

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    图标文献和实验
    该产品被引用文献

    Fibroblast Growth Factor 12 (FGF-12) is a member of the fibroblast growth factor (FGF) family. FGF-12 is probably involved in nervous system development and function. FGF-12 lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfectedinto mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.

    相关实验
    • Nature|Fgf17 如何逆转大脑衰老?

      and memory in aged mice via Fgf17. Nature (2022). 2. Castellano, J. M. et al. Human umbilical cord plasma proteins revitalize hippocampal function in aged mice. Nature 544, 488–492 (2017). 3. Fame, R. M. & Lehtinen, M. K. Emergence and developmental roles

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      也可用辅酶型维生素B 12 、辅酶 B 12 等词来表示。是由 5- 脱氧腺苷基取代氰钴胺素( CN - B 12 )中与钴连接的 CN 基而生成的,所以亦称钴胺酰胺辅酶。其中大多数是核苷酸中的碱基为 5 , 6- 二甲(基)苯并咪唑的二甲(基)苯并咪唑钴酰胺辅酶( dimeth - ylbenzimidazole cobamide coenzyme )和钴胺素辅酶,但也有碱基为腺嘌呤或 5- 羟基苯并咪唑所置换的 B 12 辅酶。 B 12 辅酶是 H.Barker 等在研

    • pc12培养

      丁香园myl0605的观点:前几天为自己养的PC12是未分化还是分化型困扰,查了一些资料,现发上来希望能给有同样问题的战友有一点帮助!培养条件:PC12细胞培养于铺有鼠尾胶原的玻璃培养瓶中,置于CO2培养箱(37℃,95%空气5%CO2),培养基选用DMEM(pH7.4,高糖),加入10%灭活小牛血清及5%灭活马血清。分化前:PC12细胞在培养基中多呈圆形,直径15~20μm,也有椭圆或多角形的,扁平的细胞少见,倾向于聚集成小团簇状(A图)。分化后:加入NGF后的24h内细胞停止分裂,长出似

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    文献支持
    Human FGF-12
    ¥640 - 17600