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Human PVR(C622)

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  • ¥840 - 17600
  • SinoBio
  • 国产
  • C622
  • 2025年12月23日
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    • 保存条件

      蛋白表达区间:Trp21-Asn343

    • 保质期

      See instructions

    • 英文名

      标签:C-6His

    • 库存

      表达系统:Human Cells

    • 供应商

      上海经科化学科技有限公司

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥840.0
    规格:50ug产品价格:¥2520.0
    规格:500ug产品价格:¥12320.0
    规格:1mg产品价格:¥17600.0
    产品描述
    Recombinant Human Poliovirus Receptor is produced by our Mammalian expression system and the target gene encoding Trp21-Asn343 is expressed with a 6His tag at the C-terminus.
    蛋白编号
    NP_006496
    产品别称
    Poliovirus Receptor; Nectin-Like Protein 5; NECL-5; CD155; PVR; PVS
    偶联
    Unconjugated
    分子量
    36.13 KDa
    表观分子量
    58 KDa, reducing conditions
    剂型描述
    Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
    内毒素
    < 1 EU/µg as determined by LAL test.
    纯度-SDS-PAGE
    Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
    生物活性-BLI
    Loaded Human TIGIT-Fc(Cat#CS92) on Protein A Biosensor, can bind Human PVR-His(Cat#C622) with an affinity constant of 4.22 nM as determined in BLI assay. (Regularly tested)
    Loaded Cynomolgus TIGIT-Fc(Cat#CW11) on Protein A Biosensor, can bind Human PVR-His(Cat#C622) with an affinity constant of 8.77 nM as determined in BLI assay. (Regularly tested)
    运输条件
    • The product is shipped on dry ice/polar packs.
    • Upon receipt, store it immediately at the temperature listed below.
    保存条件
    • Store at ≤-70°C, stable for 6 months after receipt.
    • Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
    • Please minimize freeze-thaw cycles.
    产品背景
    Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains, a transmembrane segment, and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension between epithelial cells. Alternate splicing of the PVR mRNA yields four different isoforms (α, β, γ, and δ) with identical extracellular domains.

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    图标文献和实验
    该产品被引用文献

    Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains, a transmembrane segment, and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension between epithelial cells. Alternate splicing of the PVR mRNA yields four different isoforms (α, β, γ, and δ) with identical extracellular domains.

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    文献支持
    Human PVR(C622)
    ¥840 - 17600