Application
1,2-Naphthoquinone was employed as mediator during electrochemical mapping of redox activity in normal human breast (MCF-10A) cells by scanning electrochemical microscopy (SECM).1
General description
1,2-Naphthoquinone is one of the major metabolite of naphthalene, which is responsible for the cytotoxicity and genotoxicity associated with it.2 1,2-Naphthoquinone is an atmospheric contaminant. It causes the contraction of trachea smooth muscles in guinea pig through the activation of epidermal growth factor receptor.3 1,2-Naphthoquinone has been reported as an environmental quinone in diesel exhaust particles (DEP) and atmospheric particulate matter.4
性质
Related Categories Building Blocks, C10, Carbonyl Compounds, Chemical Synthesis, Ketones,
Organic Building Blocks
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assay 97%
mp 139-142 °C (dec.)(lit.)
Gene Information human ... PTPRC(5788)