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- 详细信息
- 文献和实验
- 技术资料
- 英文名：
Aldehyde Dehydrogenase from Yeast
- 保质期：
1年
- 保存条件：
2-8°C
- 库存：
10⁺瓶
- 供应商：
上海睿安生物19121878899
- 规格：
250 Units/瓶
Roche货号10171832001醛脱氢酶19121878899上海睿安生物Merck-Sigma-Roche-Millipore官方正式授权代理商
醛脱氢酶
from yeast
别名:醛脱氢酶
属性
biological source:yeast
form:lyophilized
specific activity:~20 units/mg protein (At 25 °C with acetaldehyde as the substrate.)
packaging:pkg of 250 U
manufacturer/tradename:Roche
optimum pH:8.75
relevant disease(s):cancer
storage temp:2-8°C
说明
General description
乙醛脱氢酶（ALDH）是一种可溶性酶，活性依赖于钾离子和半胱氨酸。ALDH家族由19个人类基因组成。ALDH基因在细胞核、胞质、线粒体和内质网中表达。ALDH是烟酰胺腺嘌呤二核苷酸磷酸（NADH）和烟酰胺腺嘌呤二核苷酸磷酸（NADPH）循环系统的组成部分。
Application
乙醛脱氢酶已用于评估光纤生物传感器，从而测定液相中的乙醛（AcH）（AcH生物传感器）。
Biochem/physiol Actions
乙醛脱氢酶（ALDH）可调节非P450乙醛还原酶系统。它可保护细胞免受有毒乙醛的影响。该基因的突变与Sjogren Larsson综合征、Larsson综合征、II型高蛋白血症和癌症相关。ALDH参与了乙醛氧化成酸的反应。ALDH-2可降低因心肌梗塞或心脏手术后出现的心脏缺血。
Physical form
用磷酸钾缓冲液（pH 值约为 6）稳定酶。
Analysis Note
污染物： 分别是 <0.01%“NADH氧化酶”、ADH 和 LDH
Other Notes:仅用于生命科学研究。不可用于诊断。
同行评审论文(部分:文献)
Yeast Aldehyde Dehydrogenase II. PROPERTIES OF THE HOMOGENEOUS ENZYME PREPARATIONS
Charles R. Steinman and WILLIAM B. JAKOBY
The Journal of Biological Chemistry, 243(4), 730-734 (1965)
Improved sensitivity of acetaldehyde biosensor by detecting ADH reverse reaction-mediated NADH fluoro-quenching for wine evaluation
Iitani K, et al.
ACS sensors, 2(7), 940-946 (2017)
Gas-Phase Biosensors (Bio-Sniffers) for Measurement of 2-Nonenal, the Causative Volatile Molecule of Human Aging-Related Body Odor.
Kenta Iitani et al.
Sensors (Basel, Switzerland), 23(13) (2023-07-14)
The molecule 2-nonenal is renowned as the origin of unpleasant human aging-related body odor that can potentially indicate age-related metabolic changes. Most 2-nonenal measurements rely on chromatographic analytical systems, which pose challenges in terms of daily usage and the ability
Yeast aldehyde dehydrogenase.
S BLACK
Archives of biochemistry and biophysics, 34(1), 86-97 (1951-11-01)
Protective Effects of Facilitated Removal of Blood Alcohol and Acetaldehyde Against Liver Injury in Animal Models Fed Alcohol and Anti-HIV Drugs.
Hui Han et al.
Alcoholism, clinical and experimental research, 43(6), 1091-1102 (2019-03-26)
We previously developed enzyme nanoparticles (ENP) of alcohol metabolism. This study was to evaluate protective effects of facilitated removal of blood alcohol and/or acetaldehyde on anti-HIV drugs and alcohol-induced liver injuries. ENP were prepared for degrading alcohol completely (ENP1) or
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文献和实验该产品被引用文献
Roche货号10171832001醛脱氢酶19121878899上海睿安生物Merck-Sigma-Roche-Millipore官方正式授权代理商
醛脱氢酶
from yeast
别名:醛脱氢酶
属性
biological source:yeast
form:lyophilized
specific activity:~20 units/mg protein (At 25 °C with acetaldehyde as the substrate.)
packaging:pkg of 250 U
manufacturer/tradename:Roche
optimum pH:8.75
relevant disease(s):cancer
storage temp:2-8°C
说明
General description
乙醛脱氢酶（ALDH）是一种可溶性酶，活性依赖于钾离子和半胱氨酸。ALDH家族由19个人类基因组成。ALDH基因在细胞核、胞质、线粒体和内质网中表达。ALDH是烟酰胺腺嘌呤二核苷酸磷酸（NADH）和烟酰胺腺嘌呤二核苷酸磷酸（NADPH）循环系统的组成部分。
Application
乙醛脱氢酶已用于评估光纤生物传感器，从而测定液相中的乙醛（AcH）（AcH生物传感器）。
Biochem/physiol Actions
乙醛脱氢酶（ALDH）可调节非P450乙醛还原酶系统。它可保护细胞免受有毒乙醛的影响。该基因的突变与Sjogren Larsson综合征、Larsson综合征、II型高蛋白血症和癌症相关。ALDH参与了乙醛氧化成酸的反应。ALDH-2可降低因心肌梗塞或心脏手术后出现的心脏缺血。
Physical form
用磷酸钾缓冲液（pH 值约为 6）稳定酶。
Analysis Note
污染物： 分别是 <0.01%“NADH氧化酶”、ADH 和 LDH
Other Notes:仅用于生命科学研究。不可用于诊断。
同行评审论文(部分:文献)
Yeast Aldehyde Dehydrogenase II. PROPERTIES OF THE HOMOGENEOUS ENZYME PREPARATIONS
Charles R. Steinman and WILLIAM B. JAKOBY
The Journal of Biological Chemistry, 243(4), 730-734 (1965)
Improved sensitivity of acetaldehyde biosensor by detecting ADH reverse reaction-mediated NADH fluoro-quenching for wine evaluation
Iitani K, et al.
ACS sensors, 2(7), 940-946 (2017)
Gas-Phase Biosensors (Bio-Sniffers) for Measurement of 2-Nonenal, the Causative Volatile Molecule of Human Aging-Related Body Odor.
Kenta Iitani et al.
Sensors (Basel, Switzerland), 23(13) (2023-07-14)
The molecule 2-nonenal is renowned as the origin of unpleasant human aging-related body odor that can potentially indicate age-related metabolic changes. Most 2-nonenal measurements rely on chromatographic analytical systems, which pose challenges in terms of daily usage and the ability
Yeast aldehyde dehydrogenase.
S BLACK
Archives of biochemistry and biophysics, 34(1), 86-97 (1951-11-01)
Protective Effects of Facilitated Removal of Blood Alcohol and Acetaldehyde Against Liver Injury in Animal Models Fed Alcohol and Anti-HIV Drugs.
Hui Han et al.
Alcoholism, clinical and experimental research, 43(6), 1091-1102 (2019-03-26)
We previously developed enzyme nanoparticles (ENP) of alcohol metabolism. This study was to evaluate protective effects of facilitated removal of blood alcohol and/or acetaldehyde on anti-HIV drugs and alcohol-induced liver injuries. ENP were prepared for degrading alcohol completely (ENP1) or
文献支持
Roche货号10171832001醛脱氢酶19121878899上海睿安生物Merck-Sigma-Roche-Millipore官方正式授权代理商
￥3266.45
