Lyophilized Protein should be stored at -5℃ or lower for long term storage.
英文名:
Recombinant Human HER2 /ErbB2 /CD340 Protein, With C-Twin Strep Tag
供应商:
ACROBiosystems
规格:
25ug
PRODUCT SOURCE
Recombinant Human HER2 /ErbB2 /CD340 Protein, With C-Twin Strep Tag (rh HER2,C-Twin Strep Tag) Thr 23 - Thr 652 (Accession # AAA75493) was produced in human 293 cells (HEK293) at ACROBiosystems.
MOLECULAR CHARACTERIZATION
rh ICAM1 Fc Chimera is fused with a human IgG1 Fc tag at the C-terminus, and has a calculated MW of 75.7 kDa. The predicted N-terminus is Gln 27. DTT-reduced Protein migrates as 100-110 kDa in SDS-PAGE due to glycosylation.
BIOLOGICAL ACTIVITY
Measured by its ability to block anti-ErbB2 mediated inhibition of SK-BR-3 human breast cancer cell proliferation. The ED50 for this effect is typically 20-80 ng/mL in the presence of 0.6 μg/ml goat anti-hErbB2. Validated Herceptin Mab binding in a functional ELISA.
PURITY
>95% as determined by SDS-PAGE.
ENDOTOXIN
Less than 1.0 EU per μg of the rh HER2,C-Twin Strep Tag by the LAL method.