产品背景:
Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
产品描述:
Human Glypican 3, His Tag is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 61.7 kDa. The predicted N-terminus is Gln25, Ser359 or Val483. The reducing (R) protein migrates as 40 kDa and 60-130 kDa in SDS-PAGE due to glycosylation and associated via disulfide bonds.