活性:
Measured by its binding ability in a functional ELISA. Immobilized Human 2B4, Fc Tag (Cat# 2B4-H5255) at 5 μg/mL (100 μl/well) can bind Human CD48, His Tag (Cat# BC1-H5226 ) with a linear range of 0.04-0.4μg/mL.
产品背景:
CD48 antigen is also known as Signaling lymphocytic activation molecule 2, SLAM family member 2 (SLAMF2), Leukocyte antigen MEM-102, BCM1 surface antigen, B-lymphocyte activation marker BLAST-1. CD48 is a 65 kDa GPI-linked protein which belongs to the CD2 subfamily of immunoglobulin superfamily molecules. CD48 antigen contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domain. CD48 interacts with CD244 in an heterophilic manner. CD48 is ligand for CD2. CD48 might facilitate interaction between activated lymphocytes. CD48 is probably involved in regulating T-cell activation.
产品描述:
Human CD48, His Tag is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 23.2 kDa. The predicted N-terminus is Gln 27. The reducing (R) protein migrates as 38-45 kDa in SDS-PAGE due to glycosylation.