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Isolation and Structure Elucid

ation for Impurities (杂质分离与结构确证)
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      Isolation and Structure Elucidation for Impurities (杂质分离与结构确证)

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      天津药明康德新药开发有限公司

    Isolation and Structure Elucidation for Impurities in API and formulations:

    1. Analytical method development and preliminary confirmation of separated impurities using HPLC, LC/MS/DAD/ELSD

    2. Isolate impurity by various methods including HPLC, SPE, LLE, etc.

    3. Elucidate structure by the combination of various analytical techniques, including NMR, LC-TOF MS, EA, IR, etc.

    4. Successfully finished multiple separation and structure elucidation for commercial drugs, pharmaceutical formulations and other complex matrix

    Equipment (partial list)
    No. (set)
    NMR 400MHz
    4
    Prep-LC/MS (Waters)
    16
    Agilent LC/MS (DAD/ELSD/MS)
    10
    SHIMADZU LC/MS (DAD/MS)
    12
    HPLC (DAD/ELSD/IRD)
    15
    TOF
    1
    GC/Agilent 7890 (FID/ECD/TCD/FPD)
    1
    GC/MS
    2
    Semi-Prep SFC (DAD/MS)
    1
    ContrAA 700
    1
    Nitrogen Evaporators for Sample Concentration
    4
    VIRTIS Lyophilizer
    2
    Flash Chromatography
    5
    Thermo SpeedVac Concentrator
    6
    K - F Titrater
    1
    MIVAC Concentrator
    4
    Loystar Cyro - Freezer
    2
    LABCONCO Freeze Dryer System
    1
    Balance (d=0.1 mg and d=0.01 mg)
    6
    REVCO Low Temperature Refrigerator
    1
    Automated Liquid Handling System
    1

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    Isolation and Structure Elucidation for Impurities (杂质分离与结构确证)
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