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- 保存条件：
-20℃
- 克隆性：
单克隆
- 抗体名：
Keratin 16 (KRT16) (C-Term) 抗体
- 规格：
0.1ml/0.2ml
yb119041 产品详细信息
Keratin 16 (KRT16) (C-Term) 抗体
anti-Keratin 16 (KRT16) (C-Term) antibody
抗原
Keratin 16 (KRT16)
别名 KRT17, krt16, CK16, FNEPPK, K16, K1CP, KRT16A, NEPPK, AI324768, Krt1-16, Ka16
抗原表位
其他选择 C-Term
适用
其他选择 人
宿主
其他选择 小鼠
克隆类型 (克隆位点)
单克隆 (LL025)
标记
其他选择 非结合性
应用范围
其他选择 Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), 免疫组织化学石蜡技术（IHC-P）
Pubmed 3个引用可参考
规格 0.5 mL
发货至 中国 (更改)
发货时间 29至35个工作日
产品细节 Keratin 16 (KRT16) (C-Term) 抗体
免疫原 Synthetic peptide from the C-terminus of human cytokeratin 16
克隆位点 LL025
亚型 IgG1
特异性 This antibody is specific to a 48 kDa protein which is identified as cytokeratin 16. Cytokeratin 16 is expressed in keratinocytes which are undergoing rapid turnover in the suprabasal region. High concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation related keratins. Cellular localization: Cytoplasmic.
交叉反应 （详细） Species reactivity (tested):Human.
纯化方法 Supernatant
目标详细情况Keratin 16 (KRT16) (C-Term) 抗体
别名 Cytokeratin 16
背景 Keratin 16 is expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10 % of the invasive breast carcinomas show diffuse or focal positivity. Reportedly, a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins, but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation, and that absence of Ki-67 staining does not mean that (tumor) cells are not proliferating. Two cytokeratins, 6 and 16, are expressed when keratincytes are undergoing rapid turnover in various pathological states, wound healing, psoriasis and some carcinomas.Synonyms: CK16, Cytokeratin-16, K16, KRT16, KRT16A, Keratin 16, Keratin type I cytoskeletal 16, Keratin-16
基因ID 3868
NCBI登录号 NP_005548
UniProt P08779
研究领域 Signaling, Cytoskeleton, Cytokeratins, Extracellular Matrix
使用细节 Keratin 16 (KRT16) (C-Term) 抗体
应用备注 Immunohistochemistry: This antibody may be diluted to a titer of 1:25-1:75 in an ABC method. We suggest an incubation period of 30 minutes at room temperature. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Recommended positive control: Skin.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
贮存及处理 Keratin 16 (KRT16) (C-Term) 抗体
状态 Liquid
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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yb-0757R CDK2周期素依赖性激酶2抗体 浓度1mg/ml
yb-0633R CDK4周期素依赖性激酶4抗体 浓度1mg/ml
yb-0559R CDK5周期素依赖性激酶5抗体 浓度1mg/ml
yb-15055R C1orf2001号染色体开放阅读框200抗体 浓度1mg/ml
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yb-1028R Cytokeratin 19细胞角蛋白19抗体 浓度1mg/ml
yb-1005R CK2细胞角蛋白2抗体 浓度1mg/ml
yb-1006R CK4细胞角蛋白4抗体 浓度1mg/ml
yb-3879R Cytochrome b245 Light Chain细胞色素b245轻链抗体 浓度1mg/ml
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yb-7064R CCAR1细胞周期及凋亡调节蛋白1抗体 浓度1mg/ml
yb-0805R CD56神经细胞粘附分子1抗体 浓度1mg/ml
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yb-2034R CRIM1富含半胱氨酸运动神经元蛋白1抗体 浓度1mg/ml
yb-1660R CK5+6细胞角蛋白5+6抗体 浓度1mg/ml
yb-0842R c-Myc tagc-Myc tag标签抗体 浓度1mg/ml
yb-0848R CSP环子孢子蛋白(约氏疟原虫)抗体 浓度1mg/ml
yb-15172R C3orf30 3号染色体开放阅读框30抗体 浓度1mg/ml
yb-0811R CX3CL1CX3CL1抗体 浓度1mg/ml
yb-0488R CXorf36脱羧酶蛋白体36抗体 浓度1mg/ml
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Keratin 16 (KRT16) (C-Term) 抗体
anti-Keratin 16 (KRT16) (C-Term) antibody
抗原
Keratin 16 (KRT16)
别名 KRT17, krt16, CK16, FNEPPK, K16, K1CP, KRT16A, NEPPK, AI324768, Krt1-16, Ka16
抗原表位
其他选择 C-Term
适用
其他选择 人
宿主
其他选择 小鼠
克隆类型 (克隆位点)
单克隆 (LL025)
标记
其他选择 非结合性
应用范围
其他选择 Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), 免疫组织化学石蜡技术（IHC-P）
Pubmed 3个引用可参考
规格 0.5 mL
发货至 中国 (更改)
发货时间 29至35个工作日
产品细节 Keratin 16 (KRT16) (C-Term) 抗体
免疫原 Synthetic peptide from the C-terminus of human cytokeratin 16
克隆位点 LL025
亚型 IgG1
特异性 This antibody is specific to a 48 kDa protein which is identified as cytokeratin 16. Cytokeratin 16 is expressed in keratinocytes which are undergoing rapid turnover in the suprabasal region. High concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation related keratins. Cellular localization: Cytoplasmic.
交叉反应 （详细） Species reactivity (tested):Human.
纯化方法 Supernatant
目标详细情况Keratin 16 (KRT16) (C-Term) 抗体
别名 Cytokeratin 16
背景 Keratin 16 is expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10 % of the invasive breast carcinomas show diffuse or focal positivity. Reportedly, a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins, but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation, and that absence of Ki-67 staining does not mean that (tumor) cells are not proliferating. Two cytokeratins, 6 and 16, are expressed when keratincytes are undergoing rapid turnover in various pathological states, wound healing, psoriasis and some carcinomas.Synonyms: CK16, Cytokeratin-16, K16, KRT16, KRT16A, Keratin 16, Keratin type I cytoskeletal 16, Keratin-16
基因ID 3868
NCBI登录号 NP_005548
UniProt P08779
研究领域 Signaling, Cytoskeleton, Cytokeratins, Extracellular Matrix
使用细节 Keratin 16 (KRT16) (C-Term) 抗体
应用备注 Immunohistochemistry: This antibody may be diluted to a titer of 1:25-1:75 in an ABC method. We suggest an incubation period of 30 minutes at room temperature. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Recommended positive control: Skin.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
贮存及处理 Keratin 16 (KRT16) (C-Term) 抗体
状态 Liquid
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
yb-9921R CAMK2D钙/钙调素依赖蛋白激酶2D(CaMKIIδ) 浓度1mg/ml
yb-0372R NT5C2胞浆-5′-核苷酸酶-Ⅱ抗体 浓度1mg/ml
yb-1035R CD86CD86抗体 浓度1mg/ml
yb-0542R CDK1周期素依赖性激酶1抗体 浓度1mg/ml
yb-0757R CDK2周期素依赖性激酶2抗体 浓度1mg/ml
yb-0633R CDK4周期素依赖性激酶4抗体 浓度1mg/ml
yb-0559R CDK5周期素依赖性激酶5抗体 浓度1mg/ml
yb-15055R C1orf2001号染色体开放阅读框200抗体 浓度1mg/ml
yb-15242R c6orf2236号染色体开放阅读框223抗体 浓度1mg/ml
yb-2222R cellulase纤维素酶抗体 浓度1mg/ml
yb-8541R CLEC 4EC型凝集素4家族E抗体 浓度1mg/ml
yb-0236R ChRM2毒蕈碱型乙酰胆碱受体抗体 浓度1mg/ml
yb-0441R ChRM2毒蕈碱型乙酰胆碱受体M2抗体 浓度1mg/ml
yb-0544R CIDEB促进凋亡基因抗体 浓度1mg/ml
yb-0670R C-jun原癌基因蛋白/活化蛋白1抗体 浓度1mg/ml
yb-6796R CIDEC细胞死亡活化蛋白抗体 浓度1mg/ml
yb-1028R Cytokeratin 19细胞角蛋白19抗体 浓度1mg/ml
yb-1005R CK2细胞角蛋白2抗体 浓度1mg/ml
yb-1006R CK4细胞角蛋白4抗体 浓度1mg/ml
yb-3879R Cytochrome b245 Light Chain细胞色素b245轻链抗体 浓度1mg/ml
yb-15205R C5ORF445号染色体开放阅读框44抗体 浓度1mg/ml
yb-7685R Corin心脏特异性丝氨酸蛋白酶抗体 浓度1mg/ml
yb-7560R CPLA2胞浆型磷脂酶A2抗体 浓度1mg/ml
yb-7064R CCAR1细胞周期及凋亡调节蛋白1抗体 浓度1mg/ml
yb-0805R CD56神经细胞粘附分子1抗体 浓度1mg/ml
yb-1241R Claudin 5紧密连接蛋白5抗体 浓度1mg/ml
yb-2034R CRIM1富含半胱氨酸运动神经元蛋白1抗体 浓度1mg/ml
yb-1660R CK5+6细胞角蛋白5+6抗体 浓度1mg/ml
yb-0842R c-Myc tagc-Myc tag标签抗体 浓度1mg/ml
yb-0848R CSP环子孢子蛋白(约氏疟原虫)抗体 浓度1mg/ml
yb-15172R C3orf30 3号染色体开放阅读框30抗体 浓度1mg/ml
yb-0811R CX3CL1CX3CL1抗体 浓度1mg/ml
yb-0488R CXorf36脱羧酶蛋白体36抗体 浓度1mg/ml
yb-15183R C3orf783号染色体开放阅读框78抗体 浓度1mg/ml
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文献和实验相关实验
学依据，它为肿瘤的来源的定性，提供了理论及实物。但是，我们也应该认识到，任何事情都 不能有百分之百的准确，免疫组化的检测也一样，有时也会受到未分化细胞的制约，因此，在作出诊断前，应多做多方面的检查，结合各方面的情况，作出正确的判断。 为了更好地应用各种抗体来检测相应的抗原，下面我们将介绍常用抗体检测范围。 (一)、常用上皮组织及肿瘤标记物 角蛋白(Keratin) 角蛋白分为表皮角蛋白和细胞角蛋白两种，这是根据其分部的部位而分的。表皮角蛋白包括皮肤表皮，消化
%硫酸钠-20%硫代硫酸钠混合液固定1~3rain，或用1%戊二醛固定5min,50℃温水洗3~6min. （20）衬染：核固红衬染3min或甲基绿衬染3min. （21）常规脱水，树胶封片。 （22）镜检：阳性物质呈黑色或黑褐色，颗粒分布于抗原-抗体反应部位；背景较干净，呈红色。 （二）双PAG法的敏感性 应用本法对keratin、AFP、HBsAg、FN、SOD、HCG、F8、P53等组织抗原的定位，连续4gm石蜡切片，同时用IGSS和双PAG法，不同的一抗稀释度，结果双PAG法
,50℃温水洗3~6min. (20)衬染：核固红衬染3min或甲基绿衬染3min. (21)常规脱水，树胶封片。 (22)镜检：阳性物质呈黑色或黑褐色，颗粒分布于抗原 -抗体反应部位;背景较干净，呈红色。 (二)双PAG法的敏感性 应用本法对keratin、AFP、HBsAg、FN、SOD、HCG、F8、P53等组织抗原的定位，连续4gm石蜡切片，同时用IGSS和双PAG法，不同的一抗稀释度，结果双PAG法要比IGSS法敏感5~8倍
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Keratin 16 (KRT16) (C-Term) 抗体
询价
