yb310660 产品详细信息
Interleukin 10 Receptor, alpha (IL10RA) (N-Term) 抗体 anti-Interleukin 10 Receptor, alpha (IL10RA) (N-Term) antibody
抗原
Interleukin 10 Receptor, alpha (IL10RA)
别名 IL10R1, IL10RA, CD210, CD210a, CDW210A, HIL-10R, IL-10R1, IL10R, AW553859, CDw210, CDw210a, Il10r, mIL-10R
抗原表位
其他选择 N-Term
适用
其他选择 人
宿主
其他选择 兔
克隆类型
多克隆
标记
其他选择 非结合性
应用范围
其他选择 Western Blotting (WB)
Pubmed 找到1个引用
规格 100 μg
发货至 中国 (更改)
发货时间 9至12个工作日
产品细节 Interleukin 10 Receptor, alpha (IL10RA) (N-Term) 抗体 免疫原 Synthetic peptide directed towards the N terminal of human IL10RA
序列 GSVNLEIHNG FILGKIQLPR PKMAPANDTY ESIFSHFREY EIAIRKVPGN
预测反应 Human : 100 %, Dog : 90 %, Guinea pig : 90 %, Horse : 80 %, Bovine : 70 %, Pig : 70 %
产品特性 This is a rabbit polyclonal antibody against IL10RA. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Protein A purified
目标详细情况 Interleukin 10 Receptor, alpha (IL10RA) (N-Term) 抗体 别名 IL10RA
背景 IL10RA is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.
分子量 61 kDa
基因ID 3587
NCBI登录号 NP_001549, NM_001558
UniProt Q13651
研究领域 Immunology, Innate Immunity, Cytokines
使用细节 Interleukin 10 Receptor, alpha (IL10RA) (N-Term) 抗体 应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明
Antigen size: 578 AA
限制 仅限研究用
贮存及处理 Interleukin 10 Receptor, alpha (IL10RA) (N-Term) 抗体 状态 Lyophilized
溶解方式 Add 100 µL of distilled water.
浓度 1 mg/mL
缓冲液 PBS buffer with 2 % sucrose
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For longer periods of storage, store at -20 °C
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